Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
| ▸ | CRACR2A | Q9BSW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8492889 | 0.92 | PDE2A (0.36) | NPC1RAB9APDE2ADHODHMEN1 | |
| SCHEMBL8747828 | 0.86 | NPC1 (0.34) | NPC1RAB9APDE2ADHODHMEN1 | |
| SCHEMBL8752743 | 0.83 | DHODH (0.36) | NPC1RAB9APDE2ADHODHMEN1 | |
| SCHEMBL8492504 | 0.82 | DHODH (0.35) | RAB9APDE2ADHODHMEN1KMT2A | |
| SCHEMBL8752755 | 0.82 | DHODH (0.32) | NPC1PDE2ADHODHMEN1KMT2A | |
| SCHEMBL8489281 | 0.81 | DHODH (0.33) | RAB9APDE2ADHODHMEN1KMT2A | |
| SCHEMBL8605928 | 0.81 | DHODH (0.36) | RAB9APDE2ADHODHTAS1R3TAS1R1 | |
| SCHEMBL8488330 | 0.80 | PDE2A (0.36) | NPC1RAB9APDE2ADHODHMEN1 | |
| SCHEMBL8492849 | 0.80 | DHODH (0.36) | RAB9APDE2ADHODHMEN1KMT2A | |
| SCHEMBL8489274 | 0.80 | DHODH (0.35) | RAB9APDE2ADHODHTAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0759911-A1 | 4-BENZOYLISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1997-03-05 | — | — | EP | disclosed |
| WO-1995031446-A1 | 4-BENZOYLISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-11-23 | — | — | WO | disclosed |