SCHEMBL8747786

SCHEMBL8747786

Cc1cc(C(=O)Cl)c(O)c(C(C)(C)C)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.61
CA2 P00918 3/20 0.61
ALDH1A1 P00352 2/20 0.61
POLB P06746 1/20 0.61
TYR P14679 1/20 0.61
HSPA5 P11021 1/20 0.50
CYP2C9 P11712 4/20 0.49
CYP2C19 P33261 4/20 0.49
HIF1A Q16665 3/20 0.49
GLRA3 O75311 1/20 0.44
GLRB P48167 1/20 0.44
CYP2D6 P10635 1/20 0.44
HSD17B10 Q99714 1/20 0.44
PTGS1 P23219 1/20 0.42
PTGS2 P35354 1/20 0.42
CA1 P00915 2/20 0.42
CYP1A2 P05177 1/20 0.41
GAA P10253 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7198879 0.85 SMN1; SMN2 (0.65) SMN1; SMN2CA2ALDH1A1POLBTYR
SCHEMBL17500078 0.83 SMN1; SMN2 (0.63) SMN1; SMN2CA2ALDH1A1POLBTYR
SCHEMBL7636127 0.83 SMN1; SMN2 (0.63) SMN1; SMN2CA2ALDH1A1POLBTYR
SCHEMBL29623812 0.83 SMN1; SMN2 (0.63) SMN1; SMN2CA2ALDH1A1POLBTYR
SCHEMBL215461 0.83 SMN1; SMN2 (0.63) SMN1; SMN2CA2ALDH1A1POLBTYR
SCHEMBL29031614 0.82 SELL (0.42) SMN1; SMN2CA2ALDH1A1POLBTYR
SCHEMBL11773023 0.81 SMN1; SMN2 (0.61) SMN1; SMN2CA2ALDH1A1POLBTYR
SCHEMBL5383012 0.81 NR5A2 (0.54) SMN1; SMN2CA2ALDH1A1POLBTYR
Zinc Ion SCHEMBL11773009 0.80 SMN1; SMN2 (0.59) SMN1; SMN2CA2ALDH1A1POLBTYR
SCHEMBL10789847 0.80 SMN1; SMN2 (0.59) SMN1; SMN2CA2ALDH1A1POLBTYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0459950-B1 Stabilisation of dyes on polyamide fibres CIBA GEIGY AG (CH) 1997-03-12 EP disclosed
EP-0438381-B1 Stabilization of dyes on polyamide fibres CIBA GEIGY AG (CH) 1995-04-05 EP disclosed
US-5356443-A Treating fiber before fixation step with sterically hindered phenol and sulfo containing compound CIBA-GEIGY CORPORATION (US) 1994-10-18 US disclosed
US-5181935-A THERMAL AND PHOTOCHEMICAL STABILIZATION OF DYEINGS ON POLYAMIDE FIBERS:STERICALLY HINDERED PHENOL AND ULTRA-VIOLET ABSORBER CIBA-GEIGY CORPORATION (US) 1993-01-26 US disclosed
US-5096456-A Exhaust or continuous dyeing; carpets automotive fabrics, brassiers CIBA-GEIGY CORPORATION (US) 1992-03-17 US disclosed
EP-0459950-A1 Stabilisation of dyes on polyamide fibres CIBA-GEIGY AG (CH) 1991-12-04 EP disclosed
EP-0438381-A1 Stabilization of dyes on polyamide fibres CIBA-GEIGY AG (CH) 1991-07-24 EP disclosed