SCHEMBL5383012

SCHEMBL5383012

CC(C)(C)c1cc(C(=O)Cl)c(O)c(C(C)(C)C)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR5A2 O00482 1/20 0.54
NR5A1 Q13285 1/20 0.54
GLRA3 O75311 1/20 0.44
GLRB P48167 1/20 0.44
CA2 P00918 3/20 0.42
CA1 P00915 2/20 0.42
HSP90AA1 P07900 1/20 0.41
ALDH1A1 P00352 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
POLB P06746 1/20 0.41
TYR P14679 1/20 0.41
GAA P10253 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ALOX5 P09917 3/20 0.40
PTGS2 P35354 3/20 0.40
CYP1A2 P05177 2/20 0.40
CYP2C9 P11712 2/20 0.40
CYP2C19 P33261 2/20 0.40
CYP3A4 P08684 1/20 0.40
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8410427 0.88 GABRA1 (0.44) NR5A2NR5A1GLRA3GLRBCA2
SCHEMBL29670054 0.85 NR5A2 (0.56) NR5A2NR5A1GLRA3GLRBCA2
SCHEMBL27195660 0.85 NR5A2 (0.56) NR5A2NR5A1GLRA3GLRBCA2
SCHEMBL28742131 0.85 NR5A2 (0.56) NR5A2NR5A1GLRA3GLRBCA2
SCHEMBL30861606 0.85 NR5A2 (0.56) NR5A2NR5A1GLRA3GLRBCA2
SCHEMBL4075760 0.83 NR5A2 (0.55) NR5A2NR5A1GLRA3GLRBCA2
SCHEMBL6858504 0.83 NR5A2 (0.55) NR5A2NR5A1GLRA3GLRBCA2
SCHEMBL132940 0.83 NR5A2 (0.55) NR5A2NR5A1GLRA3GLRBCA2
SCHEMBL8747786 0.81 SMN1; SMN2 (0.61) NR5A2NR5A1GLRA3GLRBCA2
SCHEMBL9019692 0.81 NR5A2 (0.54) NR5A2NR5A1GLRA3GLRBCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230312457-A1 LOW-MIGRATION HINDERED PHENOL ANTIOXIDANT COMPOUND, PREPARATION METHOD AND COMPOSITION TSENG, JERRY (TW) 2023-10-05 US disclosed
US-20230312457-A1 LOW-MIGRATION HINDERED PHENOL ANTIOXIDANT COMPOUND, PREPARATION METHOD AND COMPOSITION TSENG, JERRY (TW) 2023-10-05 US disclosed
CN-115819238-A Low-migration hindered phenol antioxidant compound, preparation method and composition 优禘股份有限公司 2023-03-21 CN disclosed
CN-113443991-A Low-migration hindered phenol antioxidant compound, preparation method and composition 优禘股份有限公司 2021-09-28 CN disclosed
US-7232812-B2 Substituted azetidine compounds, their preparation and use as medicaments LABORATORIOS DE DR. ESTEVE S.A. (ES) 2007-06-19 US disclosed
US-20050182041-A1 Substituted Azetidine compounds, their preparation and use as medicaments LABORATOIOS DE DR. ESTEVE S.A. (ES) 2005-08-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230312457-A1 LOW-MIGRATION HINDERED PHENOL ANTIOXIDANT COMPOUND, PREPARATION METHOD AND COMPOSITION COMT, CAT, GPX4 NR5A2 2837/4885NR5A1 2131/4885GLRA3 4820/4885
US-20050182041-A1 Substituted Azetidine compounds, their preparation and use as medicaments AZI2, NISCH, QDPR NR5A2 1217/4885NR5A1 1443/4885GLRA3 2701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.