SCHEMBL8747787

SCHEMBL8747787

CC(C)c1cc(CN)cc(C(C)C)c1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.59
CA1 P00915 2/20 0.56
CA2 P00918 2/20 0.56
GABRA1 P14867 7/20 0.52
GABRB1 P18505 6/20 0.52
GABRB2 P47870 4/20 0.52
GABRA5 P31644 2/20 0.47
GABRA3 P34903 2/20 0.47
GABRA2 P47869 2/20 0.47
GABRA4 P48169 2/20 0.47
GABRA6 Q16445 2/20 0.47
MAPT P10636 1/20 0.47
DHFR P00374 1/20 0.46
FAAH O00519 1/20 0.44
LMNA P02545 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
HPGD P15428 1/20 0.44
TSHR P16473 1/20 0.44
GABRG2 P18507 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10951569 0.88 GSR (0.47) GSRCA1CA2GABRA1GABRB1
SCHEMBL2467528 0.81 GSR (0.63) GSRCA1CA2GABRA1GABRB1
SCHEMBL2854879 0.79 GSR (0.61) GSRCA1CA2GABRA1GABRB1
SCHEMBL2680058 0.79 GSR (0.61) GSRCA1CA2GABRA1GABRB1
SCHEMBL1121537 0.79 GSR (0.61) GSRCA1CA2GABRA1GABRB1
SCHEMBL20930073 0.79 GSR (0.36) GSRCA1CA2GABRA1GABRB1
SCHEMBL10821857 0.77 GSR (0.59) GSRCA1CA2GABRA1GABRB1
SCHEMBL6049696 0.77 GSR (0.59) GSRCA1CA2GABRA1GABRB1
SCHEMBL10822039 0.77 GSR (0.59) GSRCA1CA2GABRA1GABRB1
SCHEMBL9182792 0.77 GSR (0.59) GSRCA1CA2GABRA1GABRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0459950-B1 Stabilisation of dyes on polyamide fibres CIBA GEIGY AG (CH) 1997-03-12 EP disclosed
EP-0438381-B1 Stabilization of dyes on polyamide fibres CIBA GEIGY AG (CH) 1995-04-05 EP disclosed
US-5356443-A Treating fiber before fixation step with sterically hindered phenol and sulfo containing compound CIBA-GEIGY CORPORATION (US) 1994-10-18 US disclosed
US-5181935-A THERMAL AND PHOTOCHEMICAL STABILIZATION OF DYEINGS ON POLYAMIDE FIBERS:STERICALLY HINDERED PHENOL AND ULTRA-VIOLET ABSORBER CIBA-GEIGY CORPORATION (US) 1993-01-26 US disclosed
US-5096456-A Exhaust or continuous dyeing; carpets automotive fabrics, brassiers CIBA-GEIGY CORPORATION (US) 1992-03-17 US disclosed
EP-0459950-A1 Stabilisation of dyes on polyamide fibres CIBA-GEIGY AG (CH) 1991-12-04 EP disclosed
EP-0438381-A1 Stabilization of dyes on polyamide fibres CIBA-GEIGY AG (CH) 1991-07-24 EP disclosed
US-4532356-A Chemical process ETHYL CORPORATION (US) 1985-07-30 US disclosed