Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.59 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.58 |
| ▸ | GABRB1 | P18505 | 6/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.47 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10821747 | 0.88 | GSR (0.47) | GSRGABRA1GABRB1CA1CA2 | |
| SCHEMBL2680058 | 0.84 | GSR (0.61) | GSRGABRA1GABRB1CA1CA2 | |
| SCHEMBL11408652 | 0.83 | ALDH1A1 (0.43) | GSRGABRA1GABRB1CA1CA2 | |
| SCHEMBL4595014 | 0.83 | GSR (0.55) | GSRGABRA1GABRB1CA1CA2 | |
| SCHEMBL15922982 | 0.82 | GSR (0.42) | GSRGABRA1GABRB1CA1CA2 | |
| SCHEMBL2467528 | 0.81 | GSR (0.63) | GSRGABRA1GABRB1CA1CA2 | |
| SCHEMBL2854879 | 0.79 | GSR (0.61) | GSRGABRA1GABRB1CA1CA2 | |
| SCHEMBL1121537 | 0.79 | GSR (0.61) | GSRGABRA1GABRB1CA1CA2 | |
| SCHEMBL10821857 | 0.77 | GSR (0.59) | GSRGABRA1GABRB1CA1CA2 | |
| SCHEMBL8747787 | 0.77 | GSR (0.59) | GSRGABRA1GABRB1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109387574-A | A kind of separation analysis HPLC method of the phosphorus propofol sodium in relation to substance | 陕西合成药业股份有限公司 | 2019-02-26 | — | — | CN | disclosed |
| EP-1471920-A4 | PROCESS FOR PREPARING WATER-SOLUBLE PHOSPHONOOXYMETHYL DERIVATIVES OF ALCOHOL AND PHENOL | GUILFORD PHARM INC (US) | 2006-02-15 | — | — | EP | disclosed |
| EP-1471920-A2 | PROCESS FOR PREPARING WATER-SOLUBLE PHOSPHONOOXYMETHYL DERIVATIVES OF ALCOHOL AND PHENOL | GUILFORD PHARMACEUTICALS INC. (US) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003059255-A2 | PROCESS FOR PREPARING WATER-SOLUBLE PHOSPHONOOXYMETHYL DERIVATIVES OF ALCOHOL AND PHENOL | GUILFORD PHARMACEUTICALS, INC. (US) | 2003-07-24 | — | — | WO | disclosed |
| US-4317933-A | ALKYLATING TO PRODUCE AN ALDEHYDE SUBSTITUTED PHENOL, ESTERS THEREOF | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1982-03-02 | — | — | US | disclosed |
| US-4091225-A | ALKYLATION, REDUCTION, TRANSESTERIFICATION | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-05-23 | — | — | US | disclosed |