Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 19/20 | 0.43 |
| ▸ | SLC16A1 | P53985 | 16/20 | 0.43 |
| ▸ | MCTS1 | Q9ULC4 | 8/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9244003 | 0.99 | SLC16A3 (0.42) | SLC16A3SLC16A1MCTS1 | |
| SCHEMBL9243997 | 0.88 | SLC16A3 (0.35) | SLC16A3SLC16A1MCTS1 | |
| SCHEMBL9244843 | 0.88 | SLC16A3 (0.37) | SLC16A3SLC16A1MCTS1 | |
| SCHEMBL9251152 | 0.87 | SLC16A3 (0.41) | SLC16A3SLC16A1MCTS1 | |
| SCHEMBL9245590 | 0.87 | PPARA (0.38) | SLC16A3SLC16A1MCTS1 | |
| SCHEMBL9248983 | 0.86 | SLC16A3 (0.39) | SLC16A3SLC16A1MCTS1 | |
| SCHEMBL9245024 | 0.86 | SLC16A3 (0.41) | SLC16A3SLC16A1MCTS1 | |
| SCHEMBL9247301 | 0.86 | ADORA3 (0.43) | SLC16A3SLC16A1MCTS1 | |
| SCHEMBL9248341 | 0.85 | SLC16A3 (0.41) | SLC16A3SLC16A1MCTS1 | |
| SCHEMBL9247121 | 0.85 | SLC16A3 (0.46) | SLC16A3SLC16A1MCTS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0599732-B1 | Derivatives of 1-phenylbicyclo-2,2,2-octane, their preparation process and pharmaceutical compositions containing them | ADIR (FR) | 1997-03-12 | — | — | EP | claimed |
| US-5403953-A | Antiarthritic and -inflammatory agents | ADIR ET COMPAGNIE (FR) | 1995-04-04 | — | — | US | claimed |
| JP-6228044-A | — | — | None | — | — | JP | disclosed |
| US-5403953-A | Antiarthritic and -inflammatory agents | ADIR ET COMPAGNIE (FR) | 1995-04-04 | — | — | US | disclosed |
| JP-H06228044-A | NEW 1-PHENYLBICYCLO(2,2,2)OCTANE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THESE DERIVATIVES | ADIR | 1994-08-16 | — | — | JP | disclosed |
| EP-0599732-A1 | Derivatives of 1-phenylbicyclo-2,2,2-octane, their preparation process and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-06-01 | — | — | EP | disclosed |