SCHEMBL8747925

SCHEMBL8747925

CCCCCC1CCC(CCCCc2ccc(C(F)(F)F)c(F)c2)CC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.40
CYP3A4 P08684 1/20 0.38
CYP2C8 P10632 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
S1PR3 Q99500 1/20 0.38
KIF11 P52732 1/20 0.38
ITGB3 P05106 1/20 0.38
ITGA2B P08514 1/20 0.38
SPHK1 Q9NYA1 2/20 0.37
HTR2A P28223 1/20 0.37
HSD11B1 P28845 1/20 0.37
FAAH O00519 1/20 0.37
BCHE P06276 1/20 0.36
CNR2 P34972 1/20 0.36
RARB P10826 2/20 0.36
RARA P10276 1/20 0.36
RARG P13631 1/20 0.36
S1PR1 P21453 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8747948 0.99 CYP3A4 (0.40) DAOCYP3A4CYP2C8CYP2D6CYP2C9
SCHEMBL8748064 0.99 CYP3A4 (0.40) DAOCYP3A4CYP2C8CYP2D6CYP2C9
SCHEMBL8747900 0.99 CYP3A4 (0.40) DAOCYP3A4CYP2C8CYP2D6CYP2C9
SCHEMBL8030794 0.97 DAO (0.40) DAOCYP3A4CYP2C8CYP2D6CYP2C9
SCHEMBL8034216 0.95 DAO (0.40) DAOCYP3A4CYP2C8CYP2D6CYP2C9
SCHEMBL8029837 0.95 DAO (0.40) DAOCYP3A4CYP2C8CYP2D6CYP2C9
SCHEMBL8028367 0.93 CYP3A4 (0.40) DAOCYP3A4CYP2C8CYP2D6CYP2C9
SCHEMBL8747944 0.93 DAO (0.40) DAOCYP3A4CYP2C8CYP2D6CYP2C9
SCHEMBL8028344 0.93 CYP3A4 (0.40) DAOCYP3A4CYP2C8CYP2D6CYP2C9
SCHEMBL8028338 0.93 CYP3A4 (0.40) DAOCYP3A4CYP2C8CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0761799-A1 Liquid crystalline compound substituted with fluorine containing group, liquid crystal composition, and liquid crystal display device Chisso Corporation (JP) 1997-03-12 EP disclosed