Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL8748291

CCCCc1ccccc1[N+](=O)[O-].N

nearest known ligand 0.56

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.56
TSHR P16473 1/20 0.56
HPGD P15428 1/20 0.51
LMNA P02545 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
PDE4A P27815 1/20 0.48
PDE4B Q07343 1/20 0.48
PDE4C Q08493 1/20 0.48
PDE4D Q08499 1/20 0.48
PDE3B Q13370 1/20 0.48
PDE3A Q14432 1/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
HSD17B10 Q99714 1/20 0.47
SIGMAR1 Q99720 2/20 0.47
ACHE P22303 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6679612 0.98 ALDH1A1 (0.58) ALDH1A1TSHRHPGDLMNASMN1; SMN2
SCHEMBL30543045 0.98 ALDH1A1 (0.58) ALDH1A1TSHRHPGDLMNASMN1; SMN2
SCHEMBL30543046 0.98 ALDH1A1 (0.58) ALDH1A1TSHRHPGDLMNASMN1; SMN2
SCHEMBL2244893 0.93 ALDH1A1 (0.56) ALDH1A1TSHRHPGDLMNASMN1; SMN2
SCHEMBL6398343 0.91 ALDH1A1 (0.55) ALDH1A1TSHRHPGDLMNASMN1; SMN2
SCHEMBL29350218 0.91 ALDH1A1 (0.55) ALDH1A1TSHRHPGDLMNASMN1; SMN2
SCHEMBL27782985 0.91 ALDH1A1 (0.55) ALDH1A1TSHRHPGDLMNASMN1; SMN2
SCHEMBL30668793 0.91 ALDH1A1 (0.55) ALDH1A1TSHRHPGDLMNASMN1; SMN2
SCHEMBL6686635 0.91 ALDH1A1 (0.55) ALDH1A1TSHRHPGDLMNASMN1; SMN2
SCHEMBL28031451 0.91 ALDH1A1 (0.55) ALDH1A1TSHRHPGDLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1059668-C Process for preparing N-aliphatic substituted P-phenylenediamines MONSANTO CO (US) 2000-12-20 CN disclosed
EP-0641308-B1 PROCESS FOR PREPARING N-ALIPHATIC SUBSTITUTED P-PHENYLENEDIAMINES MONSANTO CO (US) 1997-03-12 EP disclosed
EP-0641308-A1 PROCESS FOR PREPARING N-ALIPHATIC SUBSTITUTED P-PHENYLENEDIAMINES. MONSANTO CO (US) 1995-03-08 EP disclosed
WO-1993024443-A1 PROCESS FOR PREPARING N-ALIPHATIC SUBSTITUTED P-PHENYLENEDIAMINES MONSANTO COMPANY (US) 1993-12-09 WO disclosed
US-5252737-A Process for preparing N-aliphatic substituted p-phenylenediamines MONSANTO COMPANY (US) 1993-10-12 US disclosed