Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 1/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | STK17B | O94768 | 1/20 | 0.38 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30590460 | 0.83 | CACNA1H (0.46) | CACNA1HCACNA1BCACNA1CKDM4ELMNA | |
| SCHEMBL1815335 | 0.82 | CACNA1H (0.45) | CACNA1HCACNA1BCACNA1CKDM4ELMNA | |
| SCHEMBL19954225 | 0.82 | CACNA1H (0.45) | CACNA1HCACNA1BCACNA1CKDM4ELMNA | |
| SCHEMBL20630527 | 0.80 | CACNA1H (0.43) | CACNA1HCACNA1BCACNA1CKDM4ELMNA | |
| SCHEMBL19339578 | 0.76 | L3MBTL1 (0.41) | CACNA1HCACNA1BCACNA1CKDM4ELMNA | |
| SCHEMBL30590468 | 0.74 | CACNA1H (0.51) | CACNA1HCACNA1BCACNA1CKDM4ELMNA | |
| SCHEMBL15244694 | 0.74 | CACNA1B (0.56) | CACNA1HCACNA1BCACNA1CKDM4ELMNA | |
| SCHEMBL3794186 | 0.74 | L3MBTL1 (0.48) | CACNA1HCACNA1BCACNA1CKDM4ELMNA | |
| SCHEMBL29475670 | 0.73 | CACNA1H (0.53) | CACNA1HCACNA1BCACNA1CKDM4ELMNA | |
| SCHEMBL26361446 | 0.73 | CACNA1H (0.53) | CACNA1HCACNA1BCACNA1CKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012068234-A2 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2012-05-24 | — | — | WO | disclosed |