Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8748871 | 1.00 | RARB (0.36) | RARBTSHRTP53PDK2LTA4H | |
| SCHEMBL8748384 | 1.00 | RARB (0.36) | RARBTSHRTP53PDK2LTA4H | |
| SCHEMBL8748613 | 0.99 | RARB (0.37) | RARBTSHRTP53PDK2LTA4H | |
| SCHEMBL8748834 | 0.96 | RARB (0.40) | RARBTSHRPDK2LTA4HCYP1A2 | |
| SCHEMBL8748230 | 0.89 | L3MBTL1 (0.35) | TSHRCYP1A2CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL8748388 | 0.86 | CYP1A2 (0.45) | RARBTSHRPDK2LTA4HCYP1A2 | |
| SCHEMBL8748873 | 0.86 | CYP1A2 (0.45) | RARBTSHRPDK2LTA4HCYP1A2 | |
| SCHEMBL8748429 | 0.86 | CYP1A2 (0.45) | RARBTSHRPDK2LTA4HCYP1A2 | |
| SCHEMBL8748617 | 0.85 | CYP1A2 (0.46) | RARBTSHRPDK2LTA4HCYP1A2 | |
| SCHEMBL8748914 | 0.84 | TP53 (0.36) | RARBTSHRTP53PDK2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754685-A2 | Derivatives from alkoxyalkoxy substituted nitrogen containing hetero rings | Rolic AG (CH) | 1997-01-22 | — | — | EP | disclosed |