Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SELL | P14151 | 1/20 | 0.32 |
| ▸ | SELP | P16109 | 1/20 | 0.32 |
| ▸ | SELE | P16581 | 1/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2601901 | 0.97 | ALDH1A1 (0.37) | ALDH1A1TSHRKDM4EHTTSMN1; SMN2 | |
| Water SCHEMBL3791699 | 0.93 | ALDH1A1 (0.35) | ALDH1A1TSHRKDM4EHTTSMN1; SMN2 | |
| Bromide SCHEMBL11433606 | 0.93 | ALDH1A1 (0.35) | ALDH1A1TSHRKDM4EHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7252277 | 0.93 | KDM4E (0.38) | ALDH1A1TSHRKDM4EHTTSMN1; SMN2 | |
| SCHEMBL5159873 | 0.76 | KDM4E (0.50) | ALDH1A1TSHRKDM4EHTTSMN1; SMN2 | |
| SCHEMBL10679825 | 0.72 | IDO1 (0.31) | — | |
| SCHEMBL18230630 | 0.71 | GAA (0.45) | ALDH1A1SMN1; SMN2RAPGEF4 | |
| SCHEMBL25447157 | 0.67 | KDM4E (0.39) | ALDH1A1KDM4EHTTSMN1; SMN2ACHE | |
| Iodide SCHEMBL31265537 | 0.67 | MAPT (0.44) | ALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL138421 | 0.67 | ALDH1A1 (0.35) | ALDH1A1TSHRSELLSELPSELE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5494572-A | SOLVENT EXTRACTION WITH PYRIDINIUM SALT | GENERAL SEKIYU KABUSHIKIKAISHA (JP) | 1996-02-27 | — | — | US | claimed |
| CN-107580613-B | Fluoroelastomer composition | 索尔维特殊聚合物意大利有限公司 | 2020-11-13 | — | — | CN | disclosed |
| CN-106147754-B | Polystyrene substituted pyridine compound as G-quadruplex nucleic acid fluorescent probe | 广东工业大学 | 2020-03-06 | — | — | CN | disclosed |
| US-20180142050-A1 | FLUOROELASTOMER COMPOSITION | SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) | 2018-05-24 | — | — | US | disclosed |
| EP-3294801-A1 | FLUOROELASTOMER COMPOSITION | Solvay Specialty Polymers Italy S.p.A. (IT) | 2018-03-21 | — | — | EP | disclosed |
| WO-2016180660-A1 | FLUOROELASTOMER COMPOSITION | SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) | 2016-11-17 | — | — | WO | disclosed |
| EP-0653477-B1 | Use of an organic solvent for denitrogenationation of light oil by extraction | GEN SEKIYU KABUSHIKI KAISHA (JP) | 1997-03-12 | — | — | EP | disclosed |
| EP-0538738-B1 | Desulfurization and Decolourizing of light oil by extraction | GEN SEKIYU KABUSHIKI KAISHA (JP) | 1996-07-10 | — | — | EP | disclosed |
| US-5494572-A | SOLVENT EXTRACTION WITH PYRIDINIUM SALT | GENERAL SEKIYU KABUSHIKIKAISHA (JP) | 1996-02-27 | — | — | US | disclosed |
| EP-0653477-A2 | Desulfurization and denitration of light oil by extraction | GENERAL SEKIYU KABUSHIKI KAISHA (JP) | 1995-05-17 | — | — | EP | disclosed |
| EP-0538738-A2 | Desulfurization and Decolourizing of light oil by extraction | GENERAL SEKIYU KABUSHIKI KAISHA (JP) | 1993-04-28 | — | — | EP | disclosed |