Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.32 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11221778 | 0.98 | LPAR3 (0.44) | LPAR3LPAR2GAACYP4F2CYP4A11 | |
| SCHEMBL31208499 | 0.98 | MEN1 (0.40) | LPAR3LPAR2GAACYP4F2CYP4A11 | |
| SCHEMBL7261008 | 0.95 | LPAR3 (0.45) | LPAR3LPAR2GAACYP4F2CYP4A11 | |
| SCHEMBL18033890 | 0.93 | LPAR3 (0.48) | LPAR3LPAR2GAACYP4F2CYP4A11 | |
| SCHEMBL7358305 | 0.91 | GAA (0.38) | LPAR3LPAR2GAACYP4F2CYP4A11 | |
| SCHEMBL8898421 | 0.91 | LPAR3 (0.45) | LPAR3LPAR2GAAMEN1KMT2A | |
| SCHEMBL8899171 | 0.88 | LPAR3 (0.48) | LPAR3LPAR2GAAMEN1KMT2A | |
| SCHEMBL2244975 | 0.88 | LPAR3 (0.48) | LPAR3LPAR2GAAMEN1KMT2A | |
| SCHEMBL11330924 | 0.88 | — | — | |
| SCHEMBL6525668 | 0.86 | MEN1 (0.52) | LPAR3LPAR2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754685-A2 | Derivatives from alkoxyalkoxy substituted nitrogen containing hetero rings | Rolic AG (CH) | 1997-01-22 | — | — | EP | disclosed |