SCHEMBL8748932

SCHEMBL8748932

CCCCCCCCCCCOC(=O)[C@@H]1CCC(=O)N1

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.49
DAGLA Q9Y4D2 1/20 0.49
LMNA P02545 2/20 0.48
GAA P10253 1/20 0.46
NAAA Q02083 3/20 0.44
PPARG P37231 3/20 0.40
TSHR P16473 2/20 0.40
HSD17B10 Q99714 1/20 0.39
EPHX1 P07099 1/20 0.39
GPR84 Q9NQS5 1/20 0.39
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8748920 1.00 CNR1 (0.49) CNR1DAGLALMNAGAANAAA
SCHEMBL10353701 1.00 CNR1 (0.49) CNR1DAGLALMNAGAANAAA
SCHEMBL3326274 1.00 CNR1 (0.49) CNR1DAGLALMNAGAANAAA
SCHEMBL1978843 1.00 CNR1 (0.49) CNR1DAGLALMNAGAANAAA
SCHEMBL1978841 1.00 CNR1 (0.49) CNR1DAGLALMNAGAANAAA
SCHEMBL7715586 1.00 CNR1 (0.49) CNR1DAGLALMNAGAANAAA
SCHEMBL9511157 1.00 CNR1 (0.49) CNR1DAGLALMNAGAANAAA
SCHEMBL10353311 1.00 CNR1 (0.49) CNR1DAGLALMNAGAANAAA
SCHEMBL3326271 1.00 CNR1 (0.49) CNR1DAGLALMNAGAANAAA
SCHEMBL130784 1.00 CNR1 (0.49) CNR1DAGLALMNAGAANAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0342056-B1 Cosmetic composition UNILEVER PLC (GB) 1994-08-17 EP claimed
EP-0277428-B1 Cosmetic composition UNILEVER PLC (GB) 1994-03-23 EP claimed
EP-0342055-B1 Use of pyroglutamic acid alkyl esters for the manufacture of a medicament for the treatment of ichthyosis UNILEVER PLC (GB) 1994-01-12 EP claimed
EP-0342054-B1 Cosmetic composition UNILEVER PLC (GB) 1993-11-03 EP claimed
EP-0342056-A2 Cosmetic composition UNILEVER PLC (GB) 1989-11-15 EP claimed
EP-0342054-A2 Cosmetic composition UNILEVER PLC (GB) 1989-11-15 EP claimed
EP-0342055-A2 Use of pyroglutamic acid alkyl esters for the manufacture of a medicament for the treatment of ichthyosis UNILEVER PLC (GB) 1989-11-15 EP claimed
EP-0277428-A2 Cosmetic composition UNILEVER PLC (GB) 1988-08-10 EP claimed
EP-0571198-B1 Cosmetic composition containing hair-growth promoter UNILEVER PLC (GB) 1997-03-19 EP disclosed
EP-0572167-B1 Cosmetic composition UNILEVER PLC (GB) 1996-10-09 EP disclosed
US-5559092-A HAIR GROWTH, GLUTAMINE DIPEPTIDE CHESEBROUGH-POND'S USA CO. DIVISION OF CONOPCO, INC. (US) 1996-09-24 US disclosed
EP-0490581-B1 Cosmetic composition UNILEVER PLC (GB) 1996-05-22 EP disclosed
EP-0517371-B1 Hair growth composition containing citric acid esters UNILEVER PLC (GB) 1996-01-10 EP disclosed
US-5358714-A Diacylglycerols as chemical activators of protein kinase C enzymes for inducing and increasing hair growth UNILEVER PATENT HOLDINGS B.V. (NL) 1994-10-25 US disclosed
US-4832946-A CELL CULTURE FOR HAIR GROWTH CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC., A CORP. OF NY 1989-05-23 US disclosed
EP-0295092-A2 Skin treatment composition UNILEVER PLC (GB) 1988-12-14 EP disclosed
US-4789667-A ANTIINFLAMMATORY AGENT AND PYROGLUTAMATES AS PENETRATION ENHANCERS TEIJIN LIMITED (JP) 1988-12-06 US disclosed
EP-0277428-A2 Cosmetic composition UNILEVER PLC (GB) 1988-08-10 EP disclosed
EP-0272920-A1 Cosmetic composition UNILEVER PLC (GB) 1988-06-29 EP disclosed
EP-0173990-A2 External pharmaceutical composition TEIJIN LIMITED (JP) 1986-03-12 EP disclosed