Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8748920 | 1.00 | CNR1 (0.49) | CNR1DAGLALMNAGAANAAA | |
| SCHEMBL10353701 | 1.00 | CNR1 (0.49) | CNR1DAGLALMNAGAANAAA | |
| SCHEMBL3326274 | 1.00 | CNR1 (0.49) | CNR1DAGLALMNAGAANAAA | |
| SCHEMBL1978843 | 1.00 | CNR1 (0.49) | CNR1DAGLALMNAGAANAAA | |
| SCHEMBL1978841 | 1.00 | CNR1 (0.49) | CNR1DAGLALMNAGAANAAA | |
| SCHEMBL7715586 | 1.00 | CNR1 (0.49) | CNR1DAGLALMNAGAANAAA | |
| SCHEMBL9511157 | 1.00 | CNR1 (0.49) | CNR1DAGLALMNAGAANAAA | |
| SCHEMBL10353311 | 1.00 | CNR1 (0.49) | CNR1DAGLALMNAGAANAAA | |
| SCHEMBL130784 | 1.00 | CNR1 (0.49) | CNR1DAGLALMNAGAANAAA | |
| SCHEMBL8748932 | 1.00 | CNR1 (0.49) | CNR1DAGLALMNAGAANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0397519-B1 | Cosmetic composition | UNILEVER PLC (GB) | 1994-11-09 | — | — | EP | claimed |
| EP-0342056-B1 | Cosmetic composition | UNILEVER PLC (GB) | 1994-08-17 | — | — | EP | claimed |
| EP-0342055-B1 | Use of pyroglutamic acid alkyl esters for the manufacture of a medicament for the treatment of ichthyosis | UNILEVER PLC (GB) | 1994-01-12 | — | — | EP | claimed |
| EP-0342054-B1 | Cosmetic composition | UNILEVER PLC (GB) | 1993-11-03 | — | — | EP | claimed |
| US-5137714-A | Anhydrous cosmetic composition comprising stable lower alkyl esters of pyroglutamic acid | UNILEVER PATENT HOLDINGS B.V. (NL) | 1992-08-11 | — | — | US | claimed |
| EP-0397519-A1 | Cosmetic composition | UNILEVER PLC (GB) | 1990-11-14 | — | — | EP | claimed |
| EP-0342054-A2 | Cosmetic composition | UNILEVER PLC (GB) | 1989-11-15 | — | — | EP | claimed |
| EP-0342055-A2 | Use of pyroglutamic acid alkyl esters for the manufacture of a medicament for the treatment of ichthyosis | UNILEVER PLC (GB) | 1989-11-15 | — | — | EP | claimed |
| EP-0342056-A2 | Cosmetic composition | UNILEVER PLC (GB) | 1989-11-15 | — | — | EP | claimed |
| EP-2121611-B1 | UV-filter compounds based on alpha,beta-dihydroxyketones | DSM IP ASSETS BV (NL) | 2015-04-15 | — | — | EP | disclosed |
| EP-2744473-A1 | SKIN ENGAGING MEMBER COMPRISING AN ANTI-IRRITATION AGENT | The Gillette Company (US) | 2014-06-25 | — | — | EP | disclosed |
| CN-103732205-A | Skin engaging member comprising an anti-irritation agent | GILLETTE CO | 2014-04-16 | — | — | CN | disclosed |
| WO-2013025857-A1 | SKIN ENGAGING MEMBER COMPRISING AN ANTI-IRRITATION AGENT | THE GILLETTE COMPANY (US) | 2013-02-21 | — | — | WO | disclosed |
| US-20130042482-A1 | Skin Engaging Member Comprising An Anti-Irritation Agent | THE GILLETTE COMPANY LLC | 2013-02-21 | — | — | US | disclosed |
| EP-0375388-A2 | Cosmetic composition | UNILEVER PLC (GB) | 1990-06-27 | — | — | EP | disclosed |
| EP-0342055-A2 | Use of pyroglutamic acid alkyl esters for the manufacture of a medicament for the treatment of ichthyosis | UNILEVER PLC (GB) | 1989-11-15 | — | — | EP | disclosed |
| EP-0342054-A2 | Cosmetic composition | UNILEVER PLC (GB) | 1989-11-15 | — | — | EP | disclosed |
| EP-0342056-A2 | Cosmetic composition | UNILEVER PLC (GB) | 1989-11-15 | — | — | EP | disclosed |
| EP-0295092-A2 | Skin treatment composition | UNILEVER PLC (GB) | 1988-12-14 | — | — | EP | disclosed |
| US-4789667-A | ANTIINFLAMMATORY AGENT AND PYROGLUTAMATES AS PENETRATION ENHANCERS | TEIJIN LIMITED (JP) | 1988-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130042482-A1 | Skin Engaging Member Comprising An Anti-Irritation Agent | CUTA, ITCH, DSG1 | CNR1 2269/4885DAGLA 90/4885LMNA 3331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.