SCHEMBL8749113

SCHEMBL8749113

CCCCOC(=O)[C@@H](N)CCC(N)=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOD1 Q9Y239 4/20 0.49
KMT2A Q03164 2/20 0.47
ALOX15 P16050 1/20 0.47
BLM P54132 1/20 0.47
PMP22 Q01453 1/20 0.47
ALDH1A1 P00352 2/20 0.44
ATM Q13315 1/20 0.41
DPP4 P27487 1/20 0.39
DPP8 Q6V1X1 1/20 0.39
DPP9 Q86TI2 1/20 0.39
MAPT P10636 1/20 0.39
RAB9A P51151 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
HSD17B10 Q99714 1/20 0.38
MEN1 O00255 1/20 0.38
FAAH O00519 1/20 0.38
TP53 P04637 1/20 0.38
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8581073 1.00 NOD1 (0.49) NOD1KMT2AALOX15BLMPMP22
SCHEMBL27956720 1.00 NOD1 (0.49) NOD1KMT2AALOX15BLMPMP22
Hydrochloric Acid SCHEMBL27709497 0.98 NOD1 (0.48) NOD1KMT2AALOX15BLMPMP22
Hydrochloric Acid SCHEMBL27497105 0.98 NOD1 (0.48) NOD1KMT2AALOX15BLMPMP22
SCHEMBL2732561 0.95 NOD1 (0.54) NOD1KMT2AALOX15BLMPMP22
SCHEMBL7050366 0.93 NOD1 (0.56) NOD1KMT2AALOX15BLMPMP22
SCHEMBL794471 0.93 NOD1 (0.56) NOD1KMT2AALOX15BLMPMP22
SCHEMBL7350344 0.93 NOD1 (0.56) NOD1KMT2AALOX15BLMPMP22
SCHEMBL7780347 0.93 NOD1 (0.56) NOD1KMT2AALOX15BLMPMP22
SCHEMBL7775110 0.93 NOD1 (0.56) NOD1KMT2AALOX15BLMPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107365295-B Improved method of pomalidomide synthesis process 常州制药厂有限公司 2020-07-07 CN disclosed
CN-104016967-A Synthetic method of pomalidomide NANJING UNIVERSITY OF TECHNOLOGY 2014-09-03 CN disclosed
CN-103819454-A Preparation method of N-(2, 6-dioxo-3-piperidyl) phthalimide compound NANJING HUAWE MEDICAL TECHNOLOGY DEV CO LTD 2014-05-28 CN disclosed
EP-0571198-B1 Cosmetic composition containing hair-growth promoter UNILEVER PLC (GB) 1997-03-19 EP disclosed
EP-0572167-B1 Cosmetic composition UNILEVER PLC (GB) 1996-10-09 EP disclosed