Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.41 |
| ▸ | GSK3A | P49840 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4619073 | 0.90 | KAT2B (0.51) | KAT2BTSHRTDP1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL5063788 | 0.88 | KAT2B (0.54) | KAT2BTSHRTDP1ALDH1A1MAPT | |
| SCHEMBL29183738 | 0.84 | TSHR (0.52) | GPR35KAT2BTSHRTDP1ALDH1A1 | |
| SCHEMBL9367239 | 0.83 | KAT2B (0.52) | KAT2BTSHRTDP1ALDH1A1MAPT | |
| SCHEMBL125386 | 0.83 | KAT2B (0.68) | KAT2BTSHRTDP1ALDH1A1MAPT | |
| SCHEMBL29393615 | 0.83 | KAT2B (0.68) | KAT2BTSHRTDP1ALDH1A1MAPT | |
| SCHEMBL9383147 | 0.83 | KAT2B (0.49) | KAT2BTSHRTDP1ALDH1A1MAPT | |
| SCHEMBL10480286 | 0.83 | KAT2B (0.46) | KAT2BTSHRTDP1ALDH1A1MAPT | |
| SCHEMBL18340832 | 0.83 | KAT2B (0.46) | KAT2BTSHRTDP1ALDH1A1MAPT | |
| SCHEMBL9245044 | 0.82 | KAT2B (0.52) | GPR35KAT2BMAPTPKMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659399-B1 | Process of direct hair using steam | OREAL (FR) | 1997-03-19 | — | — | EP | claimed |
| US-5496377-A | HAIR DYES, NITRO-AMINE COMPOUNDS | L'OREAL (FR) | 1996-03-05 | — | — | US | claimed |
| EP-0659399-A1 | Process of direct hair using steam | L'OREAL (FR) | 1995-06-28 | — | — | EP | claimed |
| EP-0659399-B1 | Process of direct hair using steam | OREAL (FR) | 1997-03-19 | — | — | EP | disclosed |
| US-5496377-A | HAIR DYES, NITRO-AMINE COMPOUNDS | L'OREAL (FR) | 1996-03-05 | — | — | US | disclosed |
| EP-0659399-A1 | Process of direct hair using steam | L'OREAL (FR) | 1995-06-28 | — | — | EP | disclosed |