Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4619073 | 0.92 | KAT2B (0.51) | KAT2BTSHRTDP1ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL5063788 | 0.90 | KAT2B (0.54) | KAT2BTSHRTDP1ALDH1A1POLB | |
| SCHEMBL125386 | 0.84 | KAT2B (0.68) | KAT2BTSHRTDP1ALDH1A1POLB | |
| SCHEMBL29393615 | 0.84 | KAT2B (0.68) | KAT2BTSHRTDP1ALDH1A1POLB | |
| SCHEMBL9372411 | 0.83 | RAB9A (0.53) | KAT2BTSHRTDP1ALDH1A1POLB | |
| SCHEMBL28271657 | 0.83 | KAT2B (0.48) | KAT2BTSHRTDP1ALDH1A1POLB | |
| SCHEMBL10480634 | 0.83 | KAT2B (0.48) | KAT2BTSHRTDP1ALDH1A1POLB | |
| SCHEMBL29183738 | 0.83 | TSHR (0.52) | KAT2BTSHRTDP1ALDH1A1KMT2A | |
| SCHEMBL8749191 | 0.83 | GPR35 (0.50) | KAT2BTSHRTDP1ALDH1A1POLB | |
| SCHEMBL9771638 | 0.82 | KAT2B (0.56) | KAT2BTSHRTDP1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0303878-B1 | 2,5-diamino-nitro-6-pyridine derivatives containing hair dyeing agents | WELLA AG (DE) | 1994-07-13 | — | — | EP | claimed |