SCHEMBL8749261

SCHEMBL8749261

CCCCCCCC(C)OC(=O)C1CCC(=O)N1

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 2/20 0.59
DAGLA Q9Y4D2 1/20 0.59
NAAA Q02083 1/20 0.48
FAAH O00519 5/20 0.44
CNR2 P34972 1/20 0.44
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.39
CCR2 P41597 1/20 0.39
KDM4E B2RXH2 1/20 0.39
KMT2A Q03164 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.36
POLB P06746 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8749260 1.00 CNR1 (0.59) CNR1DAGLANAAAFAAHCNR2
SCHEMBL9221490 0.85 CNR1 (0.57) CNR1DAGLALMNACCR2GAA
SCHEMBL9346795 0.85 CNR1 (0.57) CNR1DAGLALMNACCR2GAA
SCHEMBL9511146 0.85 CNR1 (0.57) CNR1DAGLALMNACCR2GAA
SCHEMBL10603876 0.85 CNR1 (0.57) CNR1DAGLALMNACCR2GAA
SCHEMBL9221483 0.85 CNR1 (0.57) CNR1DAGLALMNACCR2GAA
SCHEMBL8749002 0.84 CNR1 (0.54) CNR1DAGLANAAAFAAHCNR2
SCHEMBL9347473 0.83 CNR1 (0.55) CNR1DAGLALMNACCR2GAA
SCHEMBL8749203 0.83 CNR1 (0.55) CNR1DAGLANAAAALDH1A1LMNA
SCHEMBL8749158 0.83 CNR1 (0.55) CNR1DAGLANAAAALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0342056-B1 Cosmetic composition UNILEVER PLC (GB) 1994-08-17 EP claimed
EP-0277428-B1 Cosmetic composition UNILEVER PLC (GB) 1994-03-23 EP claimed
EP-0342055-B1 Use of pyroglutamic acid alkyl esters for the manufacture of a medicament for the treatment of ichthyosis UNILEVER PLC (GB) 1994-01-12 EP claimed
EP-0342054-B1 Cosmetic composition UNILEVER PLC (GB) 1993-11-03 EP claimed
EP-0342056-A2 Cosmetic composition UNILEVER PLC (GB) 1989-11-15 EP claimed
EP-0342054-A2 Cosmetic composition UNILEVER PLC (GB) 1989-11-15 EP claimed
EP-0342055-A2 Use of pyroglutamic acid alkyl esters for the manufacture of a medicament for the treatment of ichthyosis UNILEVER PLC (GB) 1989-11-15 EP claimed
EP-0277428-A2 Cosmetic composition UNILEVER PLC (GB) 1988-08-10 EP claimed
EP-0446047-B1 Benzisothiazolinone-1-dioxide derivatives as elastase inhibitors UNILEVER PLC (GB) 1997-06-11 EP disclosed
EP-0571198-B1 Cosmetic composition containing hair-growth promoter UNILEVER PLC (GB) 1997-03-19 EP disclosed
EP-0572167-B1 Cosmetic composition UNILEVER PLC (GB) 1996-10-09 EP disclosed
US-5559092-A HAIR GROWTH, GLUTAMINE DIPEPTIDE CHESEBROUGH-POND'S USA CO. DIVISION OF CONOPCO, INC. (US) 1996-09-24 US disclosed
EP-0490581-B1 Cosmetic composition UNILEVER PLC (GB) 1996-05-22 EP disclosed
EP-0517371-B1 Hair growth composition containing citric acid esters UNILEVER PLC (GB) 1996-01-10 EP disclosed
EP-0334586-A1 Carbohydrate lactam derivatives and their use in cosmetic compositions UNILEVER PLC (GB) 1989-09-27 EP disclosed
EP-0334585-A2 Cosmetic composition UNILEVER PLC (GB) 1989-09-27 EP disclosed
US-4832946-A CELL CULTURE FOR HAIR GROWTH CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC., A CORP. OF NY 1989-05-23 US disclosed
EP-0295092-A2 Skin treatment composition UNILEVER PLC (GB) 1988-12-14 EP disclosed
EP-0277428-A2 Cosmetic composition UNILEVER PLC (GB) 1988-08-10 EP disclosed
EP-0272920-A1 Cosmetic composition UNILEVER PLC (GB) 1988-06-29 EP disclosed