Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9211736 | 1.00 | EPHX1 (0.45) | EPHX1ALDH1A1TSHRTHRBCYP1A2 | |
| SCHEMBL9204435 | 1.00 | EPHX1 (0.45) | EPHX1ALDH1A1TSHRTHRBCYP1A2 | |
| SCHEMBL9212988 | 1.00 | EPHX1 (0.45) | EPHX1ALDH1A1TSHRTHRBCYP1A2 | |
| SCHEMBL9205177 | 0.98 | — | — | |
| SCHEMBL14109090 | 0.90 | — | — | |
| SCHEMBL27513432 | 0.89 | EPHX1 (0.41) | EPHX1ALDH1A1TSHRTHRBCYP1A2 | |
| SCHEMBL9474195 | 0.89 | EPHX1 (0.41) | EPHX1ALDH1A1TSHRTHRBCYP1A2 | |
| SCHEMBL9214351 | 0.89 | EPHX1 (0.41) | EPHX1ALDH1A1TSHRTHRBCYP1A2 | |
| SCHEMBL4450962 | 0.89 | EPHX1 (0.41) | EPHX1ALDH1A1TSHRTHRBCYP1A2 | |
| SCHEMBL9950636 | 0.87 | EPHX1 (0.39) | EPHX1ALDH1A1TSHRTHRBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375393-A1 | Avermectin derivatives | MERCK & CO. INC. (US) | 1990-06-27 | — | — | EP | claimed |
| US-5639885-A | Redox amino acids and peptides containing them | UNIVERSITY OF FLORIDA (US) | 1997-06-17 | — | — | US | disclosed |
| US-5637601-A | ANTIPERSPIRANT, MYDRIATIC, ANTISECRETORY AGENTS | UNIVERSITY OF FLORIDA (US) | 1997-06-10 | — | — | US | disclosed |
| US-5618826-A | Anticholinergic compounds, compositions and methods of treatment | UNIVERSITY OF FLORIDA (US) | 1997-04-08 | — | — | US | disclosed |
| US-5618803-A | TO BRAIN | UNIVERSITY OF FLORIDA (US) | 1997-04-08 | — | — | US | disclosed |
| EP-0539493-B1 | TARGETED DRUG DELIVERY VIA PHOSPHONATE DERIVATIVES | BODOR NICHOLAS S (US) | 1997-03-26 | — | — | EP | disclosed |
| US-5610188-A | MYDRIATICS, ANTIPERSPIRANTS | UNIVERSITY OF FLORIDA (US) | 1997-03-11 | — | — | US | disclosed |
| US-5576332-A | Soft β-drenegic blocking agents | IVAX International GmbH (CH) | 1996-11-19 | — | — | US | disclosed |
| EP-0577725-A4 | TARGETED DRUG DELIVERY VIA MIXED PHOSPHATE DERIVATIVES | UNIV FLORIDA (US) | 1996-04-17 | — | — | EP | disclosed |
| US-5482961-A | Soft β-adrenergic blocking agents | IVAX International GmbH (CH) | 1996-01-09 | — | — | US | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| WO-1992000988-A1 | TARGETED DRUG DELIVERY VIA PHOSPHONATE DERIVATIVES | BODOR NICHOLAS S (US) | 1992-01-23 | — | — | WO | disclosed |
| US-5079366-A | To derivatize pharmaceutical peptides for transport across the blood/brain barrier | UNIVERSITY OF FLORIDA (US) | 1992-01-07 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |
| EP-0174956-B1 | SOFT $g(b)-ADRENERGIC BLOCKING AGENTS | BODOR, Nicholas S. (US) | 1990-08-16 | — | — | EP | disclosed |
| US-4888427-A | DIHYDROPYRIDINE-PYRIDINIUM SALT REDOX SYSTEM | UNIVERSITY OF FLORIDA (US) | 1989-12-19 | — | — | US | disclosed |
| US-4829086-A | Soft β-adrenergic blocking agents | IVAX International GmbH (CH) | 1989-05-09 | — | — | US | disclosed |
| EP-0293071-A1 | Redox amino acids and peptides containing them | UNIVERSITY OF FLORIDA (US) | 1988-11-30 | — | — | EP | disclosed |
| EP-0174956-A1 | SOFT -g(b)-ADRENERGIC BLOCKING AGENTS. | BODOR NICHOLAS S | 1986-03-26 | — | — | EP | disclosed |
| WO-1985004168-A1 | SOFT beta-ADRENERGIC BLOCKING AGENTS | BODOR NICHOLAS S | 1985-09-26 | — | — | WO | disclosed |