Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9211736 | 1.00 | EPHX1 (0.45) | EPHX1ALDH1A1TSHRTHRBCYP1A2 | |
| SCHEMBL9204435 | 1.00 | EPHX1 (0.45) | EPHX1ALDH1A1TSHRTHRBCYP1A2 | |
| SCHEMBL8749361 | 1.00 | EPHX1 (0.45) | EPHX1ALDH1A1TSHRTHRBCYP1A2 | |
| SCHEMBL9205177 | 0.98 | — | — | |
| SCHEMBL14109090 | 0.90 | — | — | |
| SCHEMBL27513432 | 0.89 | EPHX1 (0.41) | EPHX1ALDH1A1TSHRTHRBCYP1A2 | |
| SCHEMBL9474195 | 0.89 | EPHX1 (0.41) | EPHX1ALDH1A1TSHRTHRBCYP1A2 | |
| SCHEMBL9214351 | 0.89 | EPHX1 (0.41) | EPHX1ALDH1A1TSHRTHRBCYP1A2 | |
| SCHEMBL4450962 | 0.89 | EPHX1 (0.41) | EPHX1ALDH1A1TSHRTHRBCYP1A2 | |
| SCHEMBL9950636 | 0.87 | EPHX1 (0.39) | EPHX1ALDH1A1TSHRTHRBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |