Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.30 |
| ▸ | BUB1 | O43683 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15342732 | 0.89 | HSD11B1 (0.41) | HSD11B1ASGR1CHRM2CHRM1CHRM3 | |
| SCHEMBL18687576 | 0.82 | HSD11B1 (0.43) | HSD11B1ASGR1CHRM2CHRM1CHRM3 | |
| SCHEMBL21997092 | 0.82 | HSD11B1 (0.43) | HSD11B1ASGR1CHRM2CHRM1CHRM3 | |
| SCHEMBL14805518 | 0.82 | HSD11B1 (0.43) | HSD11B1ASGR1CHRM2CHRM1CHRM3 | |
| SCHEMBL24439134 | 0.80 | HSD11B1 (0.44) | HSD11B1ASGR1CHRM2CHRM1CHRM3 | |
| SCHEMBL13567986 | 0.80 | HSD11B1 (0.44) | HSD11B1ASGR1CHRM2CHRM1CHRM3 | |
| SCHEMBL16081763 | 0.80 | HSD11B1 (0.44) | HSD11B1ASGR1CHRM2CHRM1CHRM3 | |
| SCHEMBL22822421 | 0.80 | HSD11B1 (0.44) | HSD11B1ASGR1CHRM2CHRM1CHRM3 | |
| SCHEMBL31236410 | 0.80 | HSD11B1 (0.44) | HSD11B1ASGR1CHRM2CHRM1CHRM3 | |
| SCHEMBL17184415 | 0.80 | HSD11B1 (0.44) | HSD11B1ASGR1CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644872-B1 | ORNITHINE DECARBOXYLASE INHIBITING CYCLIC AMINOOXY COMPOUNDS | CIBA GEIGY AG (CH) | 1997-03-19 | — | — | EP | disclosed |
| US-5516806-A | ANTITUMOR | CIBA-GEIGY CORPORATION (US) | 1996-05-14 | — | — | US | disclosed |
| EP-0644872-A1 | ORNITHINE DECARBOXYLASE INHIBITING CYCLIC AMINOOXY COMPOUNDS. | CIBA GEIGY AG (CH) | 1995-03-29 | — | — | EP | disclosed |
| WO-1994024093-A1 | ORNITHINE DECARBOXYLASE INHIBITING CYCLIC AMINOOXY COMPOUNDS | CIBA-GEIGY AG (CH) | 1994-10-27 | — | — | WO | disclosed |