Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | ACACB | O00763 | 7/20 | 0.43 |
| ▸ | CKS1B | P61024 | 1/20 | 0.42 |
| ▸ | SKP1 | P63208 | 1/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | ACACA | Q13085 | 4/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23069631 | 0.82 | KMT2A (0.49) | DRD2NAMPTCKS1BSKP1SKP2 | |
| SCHEMBL23069633 | 0.82 | KMT2A (0.49) | DRD2NAMPTCKS1BSKP1SKP2 | |
| SCHEMBL4775473 | 0.79 | KDM1A (0.48) | DRD2NAMPTCKS1BSKP1SKP2 | |
| SCHEMBL8749693 | 0.79 | MALT1 (0.41) | DRD2NAMPTACACBCKS1BSKP1 | |
| SCHEMBL4775476 | 0.79 | KDM1A (0.48) | DRD2NAMPTCKS1BSKP1SKP2 | |
| SCHEMBL4724999 | 0.79 | KDM1A (0.48) | DRD2NAMPTCKS1BSKP1SKP2 | |
| SCHEMBL8749666 | 0.79 | MALT1 (0.41) | DRD2NAMPTACACBCKS1BSKP1 | |
| SCHEMBL8749663 | 0.79 | MALT1 (0.41) | DRD2NAMPTACACBCKS1BSKP1 | |
| SCHEMBL4724995 | 0.79 | KDM1A (0.48) | DRD2NAMPTCKS1BSKP1SKP2 | |
| SCHEMBL4724994 | 0.79 | KDM1A (0.48) | DRD2NAMPTCKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644872-B1 | ORNITHINE DECARBOXYLASE INHIBITING CYCLIC AMINOOXY COMPOUNDS | CIBA GEIGY AG (CH) | 1997-03-19 | — | — | EP | disclosed |
| US-5516806-A | ANTITUMOR | CIBA-GEIGY CORPORATION (US) | 1996-05-14 | — | — | US | disclosed |
| EP-0644872-A1 | ORNITHINE DECARBOXYLASE INHIBITING CYCLIC AMINOOXY COMPOUNDS. | CIBA GEIGY AG (CH) | 1995-03-29 | — | — | EP | disclosed |
| WO-1994024093-A1 | ORNITHINE DECARBOXYLASE INHIBITING CYCLIC AMINOOXY COMPOUNDS | CIBA-GEIGY AG (CH) | 1994-10-27 | — | — | WO | disclosed |