Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 3/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.40 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.40 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.39 |
| ▸ | ACACB | O00763 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 1/20 | 0.38 |
| ▸ | SKP1 | P63208 | 1/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8749693 | 1.00 | MALT1 (0.41) | MALT1DRD2NAMPTTPSAB1TPSD1 | |
| SCHEMBL8749666 | 1.00 | MALT1 (0.41) | MALT1DRD2NAMPTTPSAB1TPSD1 | |
| SCHEMBL8749707 | 0.79 | KMT2A (0.49) | DRD2NAMPTALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL8749404 | 0.79 | KMT2A (0.49) | DRD2NAMPTALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL8749408 | 0.79 | KMT2A (0.49) | DRD2NAMPTALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL8749647 | 0.79 | DRD2 (0.46) | MALT1DRD2NAMPTDDB1CRBN | |
| SCHEMBL2451977 | 0.78 | MALT1 (0.52) | MALT1DRD2TPSAB1TPSD1TPSG1 | |
| SCHEMBL29727448 | 0.78 | MALT1 (0.52) | MALT1DRD2TPSAB1TPSD1TPSG1 | |
| SCHEMBL8749510 | 0.76 | DRD2 (0.51) | DRD2ACACBCKS1BSKP1SKP2 | |
| SCHEMBL8749514 | 0.76 | DRD2 (0.51) | DRD2ACACBCKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644872-B1 | ORNITHINE DECARBOXYLASE INHIBITING CYCLIC AMINOOXY COMPOUNDS | CIBA GEIGY AG (CH) | 1997-03-19 | — | — | EP | disclosed |
| US-5516806-A | ANTITUMOR | CIBA-GEIGY CORPORATION (US) | 1996-05-14 | — | — | US | disclosed |
| EP-0644872-A1 | ORNITHINE DECARBOXYLASE INHIBITING CYCLIC AMINOOXY COMPOUNDS. | CIBA GEIGY AG (CH) | 1995-03-29 | — | — | EP | disclosed |
| WO-1994024093-A1 | ORNITHINE DECARBOXYLASE INHIBITING CYCLIC AMINOOXY COMPOUNDS | CIBA-GEIGY AG (CH) | 1994-10-27 | — | — | WO | disclosed |