Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 12/20 | 0.72 |
| ▸ | PGR | P06401 | 5/20 | 0.72 |
| ▸ | AR | P10275 | 4/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.68 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.55 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | TNF | P01375 | 1/20 | 0.55 |
| ▸ | IL6 | P05231 | 1/20 | 0.55 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.55 |
| ▸ | GLUL | P15104 | 1/20 | 0.55 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.55 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1032200 | 0.92 | HIF1A (0.68) | HIF1APGRARLMNASERPINA6 | |
| SCHEMBL11876524 | 0.90 | HIF1A (0.68) | HIF1APGRARLMNASERPINA6 | |
| SCHEMBL13232 | 0.90 | HIF1A (0.74) | HIF1APGRARLMNASERPINA6 | |
| SCHEMBL10428758 | 0.89 | HIF1A (0.73) | HIF1APGRARLMNASERPINA6 | |
| SCHEMBL31723329 | 0.89 | HIF1A (0.69) | HIF1APGRARLMNASERPINA6 | |
| SCHEMBL1938519 | 0.89 | HIF1A (0.69) | HIF1APGRARLMNASERPINA6 | |
| SCHEMBL5712429 | 0.88 | HIF1A (0.74) | HIF1APGRARLMNASERPINA6 | |
| SCHEMBL5087747 | 0.87 | HIF1A (0.70) | HIF1APGRARLMNASERPINA6 | |
| Prednisolone Acetate SCHEMBL8000 | 0.83 | HIF1A (1.00) | HIF1APGRARLMNASERPINA6 | |
| Prednisolone Acetate SCHEMBL13044467 | 0.83 | HIF1A (1.00) | HIF1APGRARLMNASERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2961398-A1 | MOBILIZING AGENTS AND USES THEREFOR | Mater Medical Research Institute Limited (AU) | 2016-01-06 | — | — | EP | disclosed |
| WO-2014132100-A1 | MOBILIZING AGENTS AND USES THEREFOR | MATER MEDICAL RESEARCH INSTITUTE LIMITED (AU) | 2014-09-04 | — | — | WO | disclosed |
| EP-2734211-A1 | ADENINE DERIVATIVES HAVING IMMUNOMODULATING ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY | Medestea Research & Production S.p.A. (IT) | 2014-05-28 | — | — | EP | disclosed |
| WO-2013011489-A1 | ADENINE DERIVATIVES HAVING IMMUNOMODULATING ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY | MEDESTEA RESEARCH & PRODUCTION S.P.A. (IT) | 2013-01-24 | — | — | WO | disclosed |
| EP-0765171-A1 | TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISORDERS | THE KENNEDY INSTITUTE OF RHEUMATOLOGY (GB) | 1997-04-02 | — | — | EP | disclosed |