SCHEMBL8750810

SCHEMBL8750810

CC[C@H](C)[C@H](N)C(=O)N1CCC(=O)C1

nearest known ligand 0.60

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DPP8 Q6V1X1 12/20 0.60
DPP4 P27487 12/20 0.56
DPP9 Q86TI2 10/20 0.56
DPP7 Q9UHL4 10/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9032640 0.79 DPP8 (0.82) DPP8DPP4DPP9DPP7
SCHEMBL9032632 0.79 DPP8 (0.82) DPP8DPP4DPP9DPP7
SCHEMBL355114 0.76 DPP4 (0.66) DPP8DPP4DPP9DPP7
SCHEMBL297708 0.76 DPP4 (0.66) DPP8DPP4DPP9DPP7
SCHEMBL5649501 0.76 DPP4 (0.66) DPP8DPP4DPP9DPP7
SCHEMBL24371198 0.76 HSP90AA1 (0.39) DPP8
SCHEMBL16710010 0.75 DPP4 (0.64) DPP8DPP4DPP9DPP7
SCHEMBL16578291 0.75 DPP4 (0.64) DPP8DPP4DPP9DPP7
SCHEMBL6824148 0.75 DPP4 (0.64) DPP8DPP4DPP9DPP7
SCHEMBL6824150 0.75 DPP4 (0.64) DPP8DPP4DPP9DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0764151-A2 PURIFICATION OF SERINE PROTEASE AND SYNTHETIC INHIBITORS THEREOF UNIVERSITAIRE INSTELLING ANTWERPEN (BE) 1997-03-26 EP claimed
WO-1995034538-A2 PURIFICATION OF SERINE PROTEASES AND SYNTHETIC INHIBITORS THEREOF UNIVERSITAIRE INSTELLING ANTWERPEN (BE) 1995-12-21 WO claimed