SCHEMBL8750894

SCHEMBL8750894

CCO[Si](COCC1CO1)(OCC)OCC.CO[Si](OC)(OC)C(C)OCC1CO1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.34
ALDH1A1 P00352 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
TSHR P16473 2/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5597327 0.82 SMN1; SMN2 (0.42) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL231370 0.82 ALDH1A1 (0.38) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL188031 0.82 SMN1; SMN2 (0.47) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL13260278 0.81 SMN1; SMN2 (0.43) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL188051 0.79 SMN1; SMN2 (0.36) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL3735046 0.76 SMN1; SMN2 (0.44) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL29138412 0.73 SMN1; SMN2 (0.38) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL7183177 0.73 SMN1; SMN2 (0.36) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL6633116 0.73 SMN1; SMN2 (0.36) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL232883 0.73 SMN1; SMN2 (0.36) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0513690-B1 Surface-treated substrate ASAHI GLASS CO LTD (JP) 1997-02-26 EP disclosed
EP-0513690-A2 Surface-treated substrate ASAHI GLASS COMPANY LTD. (JP) 1992-11-19 EP disclosed