Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.67 |
| ▸ | CTSL | P07711 | 9/20 | 0.65 |
| ▸ | CTSB | P07858 | 5/20 | 0.65 |
| ▸ | CTSS | P25774 | 2/20 | 0.65 |
| ▸ | CTSK | P43235 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8750885 | 0.92 | CTSL (0.66) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL7295888 | 0.92 | TACR1 (0.67) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL7269411 | 0.92 | TACR1 (0.67) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL8668091 | 0.89 | TACR1 (0.70) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL16095807 | 0.86 | TACR1 (0.70) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL8100557 | 0.86 | TACR1 (0.70) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL30688477 | 0.86 | TACR1 (0.70) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL12052836 | 0.86 | TACR1 (0.70) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL10049956 | 0.86 | TACR1 (0.70) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL30241933 | 0.86 | TACR1 (0.70) | TACR1CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561303-B1 | Conjugates of phenylalanine-glycine with antitumor substances | KUREHA CHEMICAL IND CO LTD (JP) | 1997-02-26 | — | — | EP | disclosed |
| US-5470960-A | Antitumor agents | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-11-28 | — | — | US | disclosed |
| US-5411964-A | Phenylalanine-glycine compounds having anti-tumor activity, process for preparation thereof, and pharmaceutical composition containing said compounds | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |