Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 16/20 | 0.53 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL874907 | 0.81 | NAMPT (0.47) | NAMPTCHRNA7 | |
| SCHEMBL875943 | 0.80 | NAMPT (0.48) | NAMPTCHRNA7POLB | |
| SCHEMBL3051516 | 0.80 | NAMPT (0.51) | NAMPTCHRNA7POLBABL1BCR | |
| SCHEMBL3058510 | 0.79 | NAMPT (0.51) | NAMPTCHRNA7POLBABL1BCR | |
| SCHEMBL875445 | 0.79 | NAMPT (0.46) | NAMPTCHRNA7 | |
| SCHEMBL874909 | 0.78 | CHRNA7 (0.47) | NAMPTCHRNA7POLB | |
| SCHEMBL874894 | 0.77 | NAMPT (0.46) | NAMPTCHRNA7 | |
| SCHEMBL3057576 | 0.77 | NAMPT (0.51) | NAMPTCHRNA7POLBABL1BCR | |
| SCHEMBL1568826 | 0.77 | NAMPT (0.46) | NAMPTCHRNA7POLBABL1BCR | |
| SCHEMBL3055667 | 0.76 | NAMPT (0.51) | NAMPTCHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038904-A1 | NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |