SCHEMBL8751530

SCHEMBL8751530

CCCCCC(C)(C)[Si](OC)(OC)OC

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
THRB P10828 1/20 0.32
SMPD1 P17405 3/20 0.31
LMNA P02545 1/20 0.31
FDPS P14324 10/20 0.31
GGPS1 O95749 7/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8845866 0.98 TSHR (0.36) TSHRTHRBSMPD1LMNAFDPS
SCHEMBL8845823 0.93
SCHEMBL233449 0.82
SCHEMBL26923405 0.80
SCHEMBL8751535 0.79 SMPD1 (0.31) TSHRTHRBSMPD1FDPSGGPS1
SCHEMBL2927935 0.79 TSHR (0.36) TSHRTHRBSMPD1LMNAFDPS
SCHEMBL497619 0.78 ALDH1A1 (0.46) TSHR
SCHEMBL8845936 0.77 TSHR (0.35) TSHRTHRBSMPD1FDPSGGPS1
SCHEMBL28251609 0.76 TSHR (0.38) TSHRTHRBSMPD1LMNAFDPS
SCHEMBL8845856 0.76 TSHR (0.33) TSHRTHRBSMPD1FDPSGGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0766708-A2 ORGANOMINERAL SILICATE COPOLYMER-BASED DETEREGENT BUILDER AND DETERGENT COMPOSITIONS CONTAINING SAME RHONE-POULENC CHIMIE (FR) 1997-04-09 EP claimed
WO-1996020268-A1 NON-CORROSIVE, GLASS AND TABLEWARE-PROTECTIVE ALKALINE AGENT AND DETERGENT COMPOSITION CONTAINING SAME RHONE-POULENC CHIMIE (FR) 1996-07-04 WO claimed
WO-1995035338-A2 ORGANOMINERAL SILICATE COPOLYMER-BASED DETEREGENT BUILDER AND DETERGENT COMPOSITIONS CONTAINING SAME RHONE-POULENC CHIMIE (FR) 1995-12-28 WO claimed