SCHEMBL8751548

SCHEMBL8751548

CC(C)(C)c1cc(CCCCCCCCCCCc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)cc(C(C)(C)C)c1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.57
GAA P10253 4/20 0.57
TSHR P16473 3/20 0.57
LMNA P02545 2/20 0.57
MAPK1 P28482 3/20 0.55
KMT2A Q03164 3/20 0.55
MEN1 O00255 2/20 0.55
CYP1A2 P05177 2/20 0.55
CYP3A4 P08684 2/20 0.55
BLM P54132 2/20 0.55
ATM Q13315 2/20 0.55
HIF1A Q16665 2/20 0.55
NPSR1 Q6W5P4 2/20 0.55
ALOX15 P16050 2/20 0.55
GMNN O75496 1/20 0.55
GABBR2 O75899 1/20 0.55
TP53 P04637 1/20 0.55
CYP2C9 P11712 1/20 0.55
NFKB1 P19838 1/20 0.55
CYP2C19 P33261 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18193748 1.00 ALDH1A1 (0.57) ALDH1A1GAATSHRLMNAMAPK1
SCHEMBL8751503 1.00 ALDH1A1 (0.57) ALDH1A1GAATSHRLMNAMAPK1
SCHEMBL8751502 1.00 ALDH1A1 (0.57) ALDH1A1GAATSHRLMNAMAPK1
SCHEMBL18193749 1.00 ALDH1A1 (0.57) ALDH1A1GAATSHRLMNAMAPK1
SCHEMBL8751545 1.00 ALDH1A1 (0.57) ALDH1A1GAATSHRLMNAMAPK1
SCHEMBL17588977 1.00 ALDH1A1 (0.57) ALDH1A1GAATSHRLMNAMAPK1
SCHEMBL3762751 1.00 ALDH1A1 (0.57) ALDH1A1GAATSHRLMNAMAPK1
SCHEMBL8751536 0.98 ALDH1A1 (0.59) ALDH1A1GAATSHRLMNAMAPK1
SCHEMBL283499 0.93 ALDH1A1 (0.59) ALDH1A1GAATSHRLMNAMAPK1
SCHEMBL2410411 0.92 ALDH1A1 (0.53) ALDH1A1GAATSHRLMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0546639-B1 A process for the preparation of bisphenols SHELL INT RESEARCH (NL) 1997-04-09 EP disclosed