⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3333671 | 0.80 | — | — | |
| SCHEMBL296853 | 0.73 | TSHR (0.33) | — | |
| SCHEMBL22661057 | 0.71 | TSHR (0.32) | — | |
| SCHEMBL4077060 | 0.69 | — | — | |
| SCHEMBL3351425 | 0.69 | — | — | |
| SCHEMBL707272 | 0.68 | — | — | |
| SCHEMBL705036 | 0.68 | — | — | |
| SCHEMBL6222943 | 0.68 | — | — | |
| SCHEMBL5497025 | 0.68 | — | — | |
| SCHEMBL705839 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0586241-B1 | Azasilacycloalkyl functional alkoxysilanes and azasilacycloalkyl functional tetramethyldisiloxanes | DOW CORNING (US) | 1997-04-09 | — | — | EP | disclosed |
| EP-0586240-B1 | Alkoxy endblocked polydiorganosiloxane and room temperature vulcanizable silicone elastomers made therefrom | DOW CORNING (US) | 1996-12-18 | — | — | EP | disclosed |
| EP-0586240-A2 | Alkoxy endblocked polydiorganosiloxane and room temperature vulcanizable silicone elastomers made therefrom | DOW CORNING CORPORATION (US) | 1994-03-09 | — | — | EP | disclosed |
| EP-0586241-A1 | Azasilacycloalkyl functional alkoxysilanes and azasilacycloalkyl functional tetramethyldisiloxanes | DOW CORNING CORPORATION (US) | 1994-03-09 | — | — | EP | disclosed |