Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 5/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL47075 | 0.79 | CHRM2 (0.41) | CHRNB2CHRNA7CHRNA4PARP1SCN10A | |
| SCHEMBL20327689 | 0.79 | CHRNB2 (0.41) | CHRNB2CHRNA7CHRNA4PARP1SCN10A | |
| SCHEMBL18058878 | 0.79 | CHRNB2 (0.41) | CHRNB2CHRNA7CHRNA4PARP1SCN10A | |
| SCHEMBL13505409 | 0.79 | CHRNB2 (0.41) | CHRNB2CHRNA7CHRNA4PARP1SCN10A | |
| SCHEMBL15098648 | 0.79 | CHRNB2 (0.41) | CHRNB2CHRNA7CHRNA4PARP1SCN10A | |
| SCHEMBL903826 | 0.79 | CHRNB2 (0.41) | CHRNB2CHRNA7CHRNA4PARP1SCN10A | |
| SCHEMBL1812334 | 0.79 | CHRNB2 (0.41) | CHRNB2CHRNA7CHRNA4PARP1SCN10A | |
| SCHEMBL12672828 | 0.79 | CHRM2 (0.41) | CHRNB2CHRNA7CHRNA4PARP1SCN10A | |
| SCHEMBL12139913 | 0.77 | CHRNB2 (0.40) | CHRNB2CHRNA7CHRNA4PARP1SCN10A | |
| Hydrochloric Acid SCHEMBL240506 | 0.77 | CHRNB2 (0.40) | CHRNB2CHRNA7CHRNA4PARP1SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012068234-A2 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2012-05-24 | — | — | WO | disclosed |