Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL875427 | 1.00 | TSHR (0.42) | TSHRALDH1A1MAPTLMNAUSP2 | |
| SCHEMBL534005 | 0.86 | TSHR (0.38) | TSHRALDH1A1MAPTLMNAUSP2 | |
| SCHEMBL2286811 | 0.86 | TSHR (0.38) | TSHRALDH1A1MAPTLMNAUSP2 | |
| SCHEMBL876481 | 0.83 | TSHR (0.44) | TSHRALDH1A1 | |
| SCHEMBL876483 | 0.83 | TSHR (0.44) | TSHRALDH1A1 | |
| SCHEMBL10883939 | 0.82 | TSHR (0.35) | TSHRALDH1A1 | |
| SCHEMBL10536751 | 0.82 | TSHR (0.35) | TSHRALDH1A1 | |
| SCHEMBL2861884 | 0.82 | TSHR (0.48) | TSHRALDH1A1 | |
| SCHEMBL2861887 | 0.82 | TSHR (0.48) | TSHRALDH1A1 | |
| SCHEMBL27517883 | 0.81 | TSHR (0.40) | TSHRALDH1A1MAPTLMNAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2003138-B1 | METHOD FOR PRODUCING ALDEHYDE USING BISPHOSPHITE AND GROUP 8-10 METAL COMPOUND, AND SUCH BISPHOSPHITE | KURARAY CO (JP) | 2013-10-09 | — | — | EP | claimed |
| US-7745666-B2 | Rreacting a nonconjugated diene having a double bond in an end and having from 6-20 carbon atoms with a carbon monoxide and hydrogen in the presence of a bisphosphite and a transition metal compound to provide an unsaturated acyclic aldehyde; | KURARAY CO., LTD. (JP) | 2010-06-29 | — | — | US | claimed |
| US-20090259073-A1 | Rreacting a nonconjugated diene having a double bond in an end and having from 6-20 carbon atoms with a carbon monoxide and hydrogen in the presence of a bisphosphite and a transition metal compound to provide an unsaturated acyclic aldehyde; | KURARAY CO., LTD (JP) | 2009-10-15 | — | — | US | claimed |
| US-7491850-B2 | Useful component of catalysts used in the hydroformylation of olefins with carbon monoxide and hydrogen; reaction under milder conditions | KURARAY CO., LTD. (JP) | 2009-02-17 | — | — | US | claimed |
| EP-2003138-A1 | METHOD FOR PRODUCING ALDEHYDE USING BISPHOSPHITE AND GROUP 8-10 METAL COMPOUND, AND SUCH BISPHOSPHITE | Kuraray Co., Ltd. (JP) | 2008-12-17 | — | — | EP | claimed |
| EP-2003138-B1 | METHOD FOR PRODUCING ALDEHYDE USING BISPHOSPHITE AND GROUP 8-10 METAL COMPOUND, AND SUCH BISPHOSPHITE | KURARAY CO (JP) | 2013-10-09 | — | — | EP | disclosed |
| WO-2012038197-A1 | COATING AGENT HAVING (METH)ACRYLIC POLYMERS AND COALESCENCE ADDITIVES | EVONIK RÖHM GMBH (DE) | 2012-03-29 | — | — | WO | disclosed |
| WO-2010112288-A1 | COATING AGENT, METHOD FOR PRODUCING A COATING AND COATED OBJECT | EVONIK RÖHM GMBH (DE) | 2010-10-07 | — | — | WO | disclosed |
| US-7745666-B2 | Rreacting a nonconjugated diene having a double bond in an end and having from 6-20 carbon atoms with a carbon monoxide and hydrogen in the presence of a bisphosphite and a transition metal compound to provide an unsaturated acyclic aldehyde; | KURARAY CO., LTD. (JP) | 2010-06-29 | — | — | US | disclosed |
| US-7728180-B2 | Method for producing ethers | KURARAY CO., LTD. (JP) | 2010-06-01 | — | — | US | disclosed |
| EP-1728796-B1 | BISPHOSPHITE AND PROCESS FOR PRODUCING ALDEHYDE COMPOUND WITH THE BISPHOSPHITE | KURARAY CO LTD KURASHIKI PLANT (JP) | 2010-03-17 | — | — | EP | disclosed |
| US-20090259073-A1 | Rreacting a nonconjugated diene having a double bond in an end and having from 6-20 carbon atoms with a carbon monoxide and hydrogen in the presence of a bisphosphite and a transition metal compound to provide an unsaturated acyclic aldehyde; | KURARAY CO., LTD (JP) | 2009-10-15 | — | — | US | disclosed |
| US-20070027058-A1 | Process for producing detergent molecules comprising an ether linkage from butadiene | EDWARDS CHARLES L | 2007-02-01 | — | — | US | disclosed |
| US-20070021318-A1 | Process for producing detergent molecules comprising an ether linkage from butadiene | EDWARDS CHARLES L | 2007-01-25 | — | — | US | disclosed |
| EP-1728796-A1 | BISPHOSPHITE AND PROCESS FOR PRODUCING ALDEHYDE COMPOUND WITH THE BISPHOSPHITE | Kuraray Co., Ltd., Kurashiki Plant (JP) | 2006-12-06 | — | — | EP | disclosed |
| US-7141539-B2 | Process for producing detergent molecules comprising an ether linkage from butadiene | SHELL OIL COMPANY (US) | 2006-11-28 | — | — | US | disclosed |
| US-20050037940-A1 | Process for producing detergent molecules comprising an ether linkage from butadiene | SHELL OIL COMPANY | 2005-02-17 | — | — | US | disclosed |
| US-4146738-A | ACTIVATED PALLADIUM TRIARYLPHOSPHINE CATALYST | CHEMISCHE WERKE HUELS, AKTIENGESELLSCHAFT (DE) | 1979-03-27 | — | — | US | disclosed |
| US-4078005-A | BROMINATION | CHEMISCHE WERKE HUELS AKTIENGESELLSCHAFT (DT) | 1978-03-07 | — | — | US | disclosed |
| US-3987009-A | TRANSITION METAL CATALYST COMPOSITIONS | UNION CARBIDE CORPORATION (US) | 1976-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090259073-A1 | Rreacting a nonconjugated diene having a double bond in an end and having from 6-20 carbon atoms with a carbon monoxide and hydrogen in the presence of a bisphosphite and a transition metal compound to provide an unsaturated acyclic aldehyde; | CBR1, RCN1, CYC1 | TSHR 1996/4885ALDH1A1 72/4885MAPT 4864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.