SCHEMBL8754697

SCHEMBL8754697

Cc1cc(CC=CO)ccn1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
UHRF1 Q96T88 1/20 0.42
KCNQ2 O43526 1/20 0.39
GRM5 P41594 1/20 0.35
FFAR1 O14842 1/20 0.34
DYRK1A Q13627 1/20 0.33
RECQL P46063 1/20 0.32
NOS3 P29474 1/20 0.32
NOS1 P29475 1/20 0.32
NOS2 P35228 1/20 0.32
SMARCA2 P51531 1/20 0.32
SMARCA4 P51532 1/20 0.32
FLT1 P17948 1/20 0.32
KDR P35968 1/20 0.32
WNT3A P56704 2/20 0.31
TYMS P04818 2/20 0.31
ADAMTS4 O75173 1/20 0.30
MMP13 P45452 1/20 0.30
CCNC P24863 1/20 0.30
CDK8 P49336 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8754653 0.80 CYP1A2 (0.45) RECQLNOS3NOS1NOS2TYMS
SCHEMBL6024921 0.80 UHRF1 (0.41) UHRF1KCNQ2GRM5FFAR1DYRK1A
SCHEMBL363433 0.79 UHRF1 (0.46) UHRF1KCNQ2GRM5FFAR1DYRK1A
Hydrochloric Acid SCHEMBL30527118 0.77 UHRF1 (0.45) UHRF1KCNQ2GRM5FFAR1DYRK1A
SCHEMBL17064665 0.76 UHRF1 (0.37) UHRF1KCNQ2GRM5
SCHEMBL29674439 0.74
SCHEMBL751470 0.74
SCHEMBL203588 0.74
SCHEMBL29306868 0.74 UHRF1 (0.33) UHRF1KCNQ2ADAMTS4MMP13
SCHEMBL4355540 0.73 UHRF1 (0.54) UHRF1KCNQ2GRM5FFAR1DYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5686619-A CHLORINATION OF HYDROXYALKYLPYRIDINIUM CHLORIDE WITH THIONYL CHLORIDE CYTEC TECHNOLOGY CORP. (US) 1997-11-11 US disclosed
EP-0759905-A1 CHLOROALKYL PYRIDINIUM HYDROCHLORIDE COMPOUNDS AND PROCESSES FOR THEIR PREPARATION CYTEC TECHNOLOGY CORP. (US) 1997-03-05 EP disclosed
US-5521316-A FREE-FLOWING DUSTLESS POWDER FOR AGRICULTURE CYTEC TECHNOLOGY CORP. (US) 1996-05-28 US disclosed
WO-1995032186-A1 CHLOROALKYL PYRIDINIUM HYDROCHLORIDE COMPOUNDS AND PROCESSES FOR THEIR PREPARATION CYTEC TECHNOLOGY CORP. (US) 1995-11-30 WO disclosed