Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11248929 | 0.80 | LMNA (0.57) | LMNASMN1; SMN2PDE4AKMT2ACYP1A2 | |
| SCHEMBL8432702 | 0.78 | SMN1; SMN2 (0.59) | LMNASMN1; SMN2PDE4AKMT2ACYP1A2 | |
| SCHEMBL8754688 | 0.78 | — | — | |
| SCHEMBL11320162 | 0.77 | — | — | |
| SCHEMBL10444894 | 0.75 | LMNA (0.37) | LMNASMN1; SMN2PDE4AKMT2ACYP1A2 | |
| SCHEMBL29776983 | 0.74 | LMNA (0.59) | LMNASMN1; SMN2PDE4AKMT2ACYP1A2 | |
| SCHEMBL3094873 | 0.74 | LMNA (0.59) | LMNASMN1; SMN2PDE4AKMT2ACYP1A2 | |
| SCHEMBL10444895 | 0.73 | KMT2A (0.36) | LMNASMN1; SMN2PDE4AKMT2ACYP1A2 | |
| SCHEMBL6270062 | 0.68 | KMT2A (0.50) | LMNASMN1; SMN2KMT2ACYP1A2CYP2C19 | |
| SCHEMBL10585696 | 0.68 | LMNA (0.37) | LMNAPDE4ACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449975-B1 | NON-TIN-BASED, LOW TOXICITY ANTI-FOULING AGENTS | BATTELLE MEMORIAL INSTITUTE (US) | 1997-04-23 | — | — | EP | claimed |