SCHEMBL8755

SCHEMBL8755

COc1ccc(CN)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.73
TAAR1 Q96RJ0 1/20 0.67
SLC6A4 P31645 1/20 0.61
IDO1 P14902 3/20 0.60
AGXT P21549 2/20 0.60
CA12 O43570 1/20 0.58
CA1 P00915 1/20 0.58
CA2 P00918 1/20 0.58
CA7 P43166 1/20 0.58
CA9 Q16790 1/20 0.58
CA14 Q9ULX7 1/20 0.58
ST14 Q9Y5Y6 1/20 0.56
LTA4H P09960 1/20 0.54
MAPK1 P28482 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
ALDH1A1 P00352 1/20 0.52
TP53 P04637 1/20 0.52
CYP3A4 P08684 1/20 0.52
ALOX15 P16050 1/20 0.52
TSHR P16473 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4951818 1.00 MAOB (0.73) MAOBTAAR1SLC6A4IDO1AGXT
Iodide SCHEMBL28780684 0.97 MAOB (0.70) MAOBTAAR1SLC6A4IDO1AGXT
Hydrochloric Acid SCHEMBL1715149 0.97 MAOB (0.77) MAOBTAAR1SLC6A4IDO1AGXT
Ammonia Solution, Strong SCHEMBL9173570 0.97 MAOB (0.70) MAOBTAAR1SLC6A4IDO1AGXT
Bromide SCHEMBL31513712 0.97 MAOB (0.70) MAOBTAAR1SLC6A4IDO1AGXT
Hydrochloric Acid SCHEMBL7011298 0.95 MAOB (0.68) MAOBTAAR1SLC6A4IDO1AGXT
SCHEMBL5828695 0.93 MAOB (0.70) MAOBTAAR1SLC6A4IDO1AGXT
Hypochlorous Acid SCHEMBL10950049 0.93 MAOB (0.66) MAOBTAAR1SLC6A4IDO1AGXT
SCHEMBL920324 0.93 ST14 (0.68) MAOBTAAR1SLC6A4IDO1AGXT
SCHEMBL8349967 0.91 ACHE (0.65) MAOBTAAR1SLC6A4IDO1AGXT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 16904 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122081969-A VSe-Cu2-xSe nanosheet catalysis C (sp)3) -H bond CO2Method for directionally synthesizing alpha-hydroxy/amino acid by carboxylation 2026-05-26 CN claimed
EP-4724442-A1 AGONISM-ANTAGONISM IN ENDOSOMAL TLRS BY MODULATING CHEMICAL FEATURES IN 8-OXOPURINE: PROCESS FOR PREPARATION AND APPLICATION THEREOF Council of Scientific and Industrial Research (IN) 2026-04-15 EP claimed
US-12508537-B2 Absorber agent for carbon dioxide derived from atmosphere KOBE GAKUIN EDUCATIONAL FOUNDATION (JP) 2025-12-30 US claimed
US-20250387385-A1 TREATMENT FOR GLOMERULAR DISEASES ZYDUS LIFESCIENCES LIMITED (IN) 2025-12-25 US claimed
CN-116102500-B Method for synthesizing 6-chloro-2-methyl-2H-indazole-5-amine 广东莱佛士制药技术有限公司 2025-06-24 CN claimed
EP-4565233-A1 TREATMENT FOR APLASTIC ANEMIA (AA) Zydus Lifesciences Limited (IN) 2025-06-11 EP claimed
CN-119977906-A A-site cation-regulated halide perovskite, and preparation method and application thereof 西北大学 2025-05-13 CN claimed
US-20250145472-A1 METHOD FOR GENERATING CARBON DIOXIDE KOBE GAKUIN EDUCATIONAL FOUNDATION (JP) 2025-05-08 US claimed
EP-4539934-A1 TREATMENT FOR GLOMERULAR DISEASES Zydus Lifesciences Limited (IN) 2025-04-23 EP claimed
CN-116265467-B Intermediate for synthesizing TYK2 inhibitor, and preparation method and application thereof 成都科岭源医药技术有限公司 2025-04-18 CN claimed
EP-0023385-B1 ETHANAMINE DERIVATIVES, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS BEECHAM GROUP PLC (GB) 1982-12-15 EP claimed
EP-0021636-B1 SECONDARY AMINES, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS BEECHAM GROUP PLC (GB) 1982-12-01 EP claimed
US-4338333-A ANTIOBESITY, HYPOGLYCEMIC BEECHAM GROUP LIMITED (GB) 1982-07-06 US claimed
US-4309443-A ANTI-OBESITY, HYPOGLYCEMIC BEECHAM GROUP LIMITED (GB) 1982-01-05 US claimed
US-4292411-A ORGANIC BISMUTH COMPOUND, PRIMARY OR SECONDARY AMINE S.A. PRB (BE) 1981-09-29 US claimed
EP-0025331-A1 Cinnamic acid derivatives, their preparation, and pharmaceutical compositions containing them BEECHAM GROUP PLC (GB) 1981-03-18 EP claimed
EP-0023385-A1 Ethanamine derivatives, their preparation and use in pharmaceutical compositions BEECHAM GROUP PLC (GB) 1981-02-04 EP claimed
EP-0021636-A1 Secondary amines, their preparation and use in pharmaceutical compositions BEECHAM GROUP PLC (GB) 1981-01-07 EP claimed
EP-0006735-A1 Secondary amines, their preparation, pharmaceutical compositions containing them and their use BEECHAM GROUP PLC (GB) 1980-01-09 EP claimed
US-4014892-A ANTHELMINTICS AMERICAN CYANAMID COMPANY (US) 1977-03-29 US claimed