Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8861242 | 0.99 | KDM4E (0.64) | KDM4ESMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL8755337 | 0.92 | KDM4E (0.62) | KDM4ESMN1; SMN2MEN1KMT2AL3MBTL1 | |
| Ataquimast SCHEMBL1150373 | 0.88 | KDM4E (0.65) | KDM4ESMN1; SMN2POLBMEN1KMT2A | |
| Ataquimast SCHEMBL29388447 | 0.88 | KDM4E (0.65) | KDM4ESMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL8754807 | 0.80 | KDM4E (0.58) | KDM4ESMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL8755269 | 0.79 | POLB (0.67) | KDM4ESMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL8755092 | 0.78 | KDM4E (0.56) | KDM4ESMN1; SMN2POLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8861258 | 0.78 | POLB (0.65) | KDM4ESMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL8861171 | 0.78 | OPRM1 (0.54) | KDM4ESMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL8755012 | 0.77 | POLB (0.55) | KDM4ESMN1; SMN2POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663903-B1 | 1,2-DIHYDRO-2-OXO-3-AMINO QUINOXALINE DERIVATIVES, PREPARATION THEREOF AND APPLICATION IN THERAPY | PF MEDICAMENT (FR) | 1997-04-23 | — | — | EP | claimed |