Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27469271 | 1.00 | FFAR3 (0.50) | FFAR3LCKFYNTSHRTP53 | |
| Acetic Acid SCHEMBL8835007 | 0.97 | FFAR3 (0.47) | FFAR3LCKFYNTSHRTP53 | |
| Acetic Acid SCHEMBL8834547 | 0.97 | FFAR3 (0.47) | FFAR3LCKFYNTSHRTP53 | |
| Acetic Acid SCHEMBL8834833 | 0.91 | FFAR3 (0.41) | FFAR3LCKFYNTSHRTP53 | |
| Bicarbonate SCHEMBL28488934 | 0.89 | TSHR (0.42) | FFAR3LCKFYNTSHRTP53 | |
| Acetone SCHEMBL48978 | 0.89 | TSHR (0.50) | FFAR3LCKFYNTSHRTP53 | |
| Acetic Acid SCHEMBL7044569 | 0.88 | TSHR (0.39) | FFAR3LCKFYNTSHRTP53 | |
| Acetone SCHEMBL28124568 | 0.86 | TSHR (0.47) | FFAR3LCKFYNTSHRTP53 | |
| Acetone SCHEMBL2748125 | 0.86 | TSHR (0.47) | FFAR3LCKFYNTSHRTP53 | |
| Acetone SCHEMBL29032239 | 0.86 | TSHR (0.47) | FFAR3LCKFYNTSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1010 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106478616-A | A kind of crystal form of GPR40 agonist and preparation method thereof | 江苏恒瑞医药股份有限公司 | 2017-03-08 | — | — | CN | claimed |
| CN-102010381-B | Improved preparation method of valsartan | SHANDONG NEW TIME PHARMACEUTICAL Co.,Ltd. (CN) | 2012-02-08 | — | — | CN | claimed |
| EP-4397663-A1 | 6-AMINOPYRAZOLOPYRIMIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | Japan Tobacco, Inc. (JP) | 2024-07-10 | — | — | EP | disclosed |
| CN-115850249-B | Triazine derivative with virus proliferation inhibition effect and pharmaceutical composition containing triazine derivative | 盐野义制药株式会社 | 2024-07-02 | — | — | CN | disclosed |
| CN-112469707-B | Preventive or therapeutic agent for spinal muscular atrophy | 利伯纳生物科学株式会社 | 2024-06-21 | — | — | CN | disclosed |
| US-12012410-B2 | Substituted pyrazolo[1,5-a]pyrazines for spinal muscular atrophy | REBORNA BIOSCIENCES, INC. (JP) | 2024-06-18 | — | — | US | disclosed |
| EP-3802530-B1 | HETEROCYCLIC COMPOUNDS AS CLASS II PHOSPHOINOSITIDE 3-KINASE INHIBITORS | FORSCHUNGSVERBUND BERLIN EV (DE) | 2024-05-29 | — | — | EP | disclosed |
| CN-118076620-A | Process for producing 2' -modified pyrimidine nucleoside | 日产化学株式会社 | 2024-05-24 | — | — | CN | disclosed |
| EP-3661923-B1 | N-HETEROCYCLIC COMPOUNDS AS OREXIN 2 AGONISTS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | TAKEDA PHARMACEUTICALS CO (JP) | 2024-05-15 | — | — | EP | disclosed |
| CN-110799190-B | Heterocyclic compounds | 卡都瑞恩医药有限公司 | 2024-04-19 | — | — | CN | disclosed |
| US-11958845-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-04-16 | — | — | US | disclosed |
| US-4064254-A | ANTIARRHYTHMIC AND ANTISEROTONINE AGENTS | MEAD JOHNSON & COMPANY (US) | 1977-12-20 | — | — | US | disclosed |
| US-4056526-A | ANALGESIC, ANTIPYRETIC, ANTIINFLAMMATORY | WARNER-LAMBERT COMPANY (US) | 1977-11-01 | — | — | US | disclosed |
| US-4033981-A | ANTIHISTOMINIC, ANTIINFLAMMATORY, SEDATIVES, DIURETICS | WARNER-LAMBERT COMPANY (US) | 1977-07-05 | — | — | US | disclosed |
| US-4018793-A | ANALGESICS, ANTIINFLAMMATORY, ANTIPYRETICS | WARNER-LAMBERT COMPANY (US) | 1977-04-19 | — | — | US | disclosed |
| US-4000143-A | ANTIARRHYTHMIC AND ANTISEROTONIN AGENTS | MEAD JOHNSON & COMPANY (US) | 1976-12-28 | — | — | US | disclosed |
| US-3992376-A | ANTIHISTAMINES, ANTITUSSIVES, SEDATIVES, ANTIINFLAMMATORY AGENTS AND DIURETICS | WARNER-LAMBERT COMPANY (US) | 1976-11-16 | — | — | US | disclosed |
| US-3978052-A | ANTIHISTAMINIC, ANTITUSSIVE, ANTIINFLAMMATORY, DIURETIC | WARNER-LAMBERT COMPANY (US) | 1976-08-31 | — | — | US | disclosed |
| US-3971814-A | ANALGESICS, ANTIPYRETICS, ANTIINFLAMMATORY AGENTS | WARNER-LAMBERT COMPANY (US) | 1976-07-27 | — | — | US | disclosed |
| US-3953464-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | WARNER-LAMBERT COMPANY (US) | 1976-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12012410-B2 | Substituted pyrazolo[1,5-a]pyrazines for spinal muscular atrophy | SMN1; SMN2, HDAC5, PUM1 | FFAR3 3541/4885LCK 4631/4885FYN 3313/4885 |
| US-11958845-B2 | Heterocyclic compound | HDAC6, HDAC1, HDAC5 | FFAR3 4277/4885LCK 2065/4885FYN 343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.