Acetone

Acetone

SCHEMBL48978

CC(C)=O.CC(C)OC(C)C

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.50
LMNA P02545 2/20 0.46
ALDH1A1 P00352 3/20 0.35
TDP1 Q9NUW8 1/20 0.35
TP53 P04637 1/20 0.33
THPO P40225 1/20 0.33
FFAR3 O14843 1/20 0.33
LCK P06239 1/20 0.33
FYN P06241 1/20 0.33
HCAR2 Q8TDS4 1/20 0.32
CA1 P00915 1/20 0.31
ALOX15 P16050 1/20 0.31
BLM P54132 1/20 0.31
PMP22 Q01453 1/20 0.31
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM1 P11229 1/20 0.31
TBXA2R P21731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetone SCHEMBL29032239 0.96 TSHR (0.47) TSHRLMNAALDH1A1TDP1TP53
Acetone SCHEMBL2748125 0.96 TSHR (0.47) TSHRLMNAALDH1A1TDP1TP53
Acetone SCHEMBL28124568 0.96 TSHR (0.47) TSHRLMNAALDH1A1TDP1TP53
Acetic Acid SCHEMBL8834547 0.93 FFAR3 (0.47) TSHRLMNAALDH1A1TDP1TP53
Acetone SCHEMBL11747870 0.93 TSHR (0.45) TSHRLMNAALDH1A1TDP1TP53
Acetic Acid SCHEMBL87553 0.89 FFAR3 (0.50) TSHRLMNAALDH1A1TDP1TP53
Acetic Acid SCHEMBL27469271 0.89 FFAR3 (0.50) TSHRLMNAALDH1A1TDP1TP53
Acetone SCHEMBL11413386 0.87 TSHR (0.41) TSHRLMNAALDH1A1TDP1BLM
Acetic Acid SCHEMBL8835007 0.86 FFAR3 (0.47) TSHRLMNAALDH1A1TDP1TP53
Acetamide SCHEMBL27400127 0.86 LMNA (0.53) TSHRLMNAALDH1A1TDP1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107602546-B Crystal form of compound, preparation method, composition and application thereof 武汉朗来科技发展有限公司 2022-04-22 CN claimed
CN-113929661-A Dabigatran etexilate intermediate and preparation method thereof 石药集团恩必普药业有限公司 2022-01-14 CN claimed
CN-109438514-B Preparation method of adefovir dipivoxil 湖南方盛制药股份有限公司 2020-12-18 CN claimed
US-10646832-B2 High selectivity copolyimide membranes for separations UOP LLC 2020-05-12 US claimed
EP-3348546-B1 CRYSTALLINE FORM OF ANDROGEN RECEPTOR INHIBITOR AND PREPARATION METHOD THEREOF JIANGSU HENGRUI MEDICINE CO (CN) 2020-04-29 EP claimed
EP-3348546-A1 CRYSTALLINE FORM OF ANDROGEN RECEPTOR INHIBITOR AND PREPARATION METHOD THEREOF Jiangsu Hengrui Medicine Co., Ltd. (CN) 2018-07-18 EP claimed
US-20180050309-A1 HIGH SELECTIVITY COPOLYIMIDE MEMBRANES FOR SEPARATIONS UOP LLC 2018-02-22 US claimed
CN-107602546-A Crystal formation of compound and preparation method thereof, composition and application 武汉朗来科技发展有限公司 2018-01-19 CN claimed
CN-107001284-A A kind of crystal form of androgen receptor inhibitor and preparation method thereof 江苏恒瑞医药股份有限公司 2017-08-01 CN claimed
US-9669363-B2 High permeance membranes for gas separations UOP LLC (US) 2017-06-06 US claimed
US-20080200668-A1 Industrial Process for the Preparation of 17-Hydroxy-6Beta, 7Beta; 15Beta, 16Beta-Bismethylene-3-Oxo-17Alpha-Pregn-4-Ene-21-Carboxylic Acid Y-Lactone and Key Intermediates for this Process RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 2008-08-21 US claimed
US-20080194812-A1 Process for the Preparation of 17-Hydroxy-6Beta, 7Beta; 15Beta, 16Beta-Bismethylene- 17Alpha-Pregn-4-Ene-3-One-21-Carboxylic Acid Y-Lactone and Key Intermediates for this Process RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 2008-08-14 US claimed
US-20080142440-A1 Liquid Separations Using High Performance Mixed Matrix Membranes UOP LLC 2008-06-19 US claimed
CN-101061132-A Process for the preparation of 17-hydroxy-6 beta, 7 beta, 15 beta, 16 beta-dimethylene-17 alpha-pregn-4-en-3-one-21-carboxylic acid gamma-lactone and key intermediates used in the process RICHTER GEDEON VEGYZETI GYAR R (HU) 2007-10-24 CN claimed
CN-101061133-A Industrial process for the preparation of 17-hydroxy-6 beta, 7 beta, 15 beta, 16 beta-dimethylene-3-oxo-17 alpha pregn-4-ene-21-carboxylic acid gamma-lactone and key intermediates used in the process RICHTER GEDEON VEGYZETI GYAR R (HU) 2007-10-24 CN claimed
EP-1817326-A1 INDUSTRIAL PROCESS FOR THE PREPERATION OF 17-HYDROXY -6 BETA, 7-BETA, 15-BETA, 16-BETA-BISMETHYLENE-3-OXO 17-ALPHA PREGN-4-ENE-21-CARBOXYLIC ACID GAMMA-LACTONE AND KEY INTERMEDIATES FOR THIS PROCESS Richter Gedeon Vegy Szeti Gy R Rt. (HU) 2007-08-15 EP claimed
WO-2006059167-A1 INDUSTRIAL PROCESS FOR THE PREPARATION OF 17-HYDROXY-6β,7β;15β,16β-BISMETHYLENE-3-OXO-17α-PREGN-4-ENE-21-CARBOXYLIC ACID Ϝ-LACTONE AND KEY-INTERMEDIATES FOR THIS PROCESS Richter Gedeon Vegyészeti Gyár Rt. (HU) 2006-06-08 WO claimed
CN-1183151-C Spherical telithromycikn clusters, method for the production and use thereof in the preparation of pharmaceutical forms ���ĵ�˹ҩƷ��˾ 2005-01-05 CN claimed
EP-1212336-B1 METHOD FOR THE PRODUCTION AND USE OF SPHERICAL TELITHROMYCIN CLUSTERS IN THE PREPARATION OF PHARMACEUTICAL FORMS AVENTIS PHARMA SA (FR) 2003-12-03 EP claimed
CN-1371386-A Spherical telithromycikn clusters, method for the production and use thereof in the preparation of pharmaceutical forms AVENTIS PHARMA SA (FR) 2002-09-25 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080200668-A1 Industrial Process for the Preparation of 17-Hydroxy-6Beta, 7Beta; 15Beta, 16Beta-Bismethylene-3-Oxo-17Alpha-Pregn-4-Ene-21-Carboxylic Acid Y-Lactone and Key Intermediates for this Process HSD17B7, CYP17A1, HSD17B11 TSHR 2195/4885LMNA 2502/4885ALDH1A1 661/4885
US-20080194812-A1 Process for the Preparation of 17-Hydroxy-6Beta, 7Beta; 15Beta, 16Beta-Bismethylene- 17Alpha-Pregn-4-Ene-3-One-21-Carboxylic Acid Y-Lactone and Key Intermediates for this Process CYP17A1, HSD17B7, HSD17B11 TSHR 2431/4885LMNA 1403/4885ALDH1A1 616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.