Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL875584 | 1.00 | S1PR3 (0.31) | S1PR3CA1CA2 | |
| SCHEMBL875583 | 1.00 | S1PR3 (0.31) | S1PR3CA1CA2 | |
| SCHEMBL10072351 | 0.94 | — | — | |
| SCHEMBL883482 | 0.93 | KCNN4 (0.33) | — | |
| SCHEMBL10072343 | 0.93 | CHRM1 (0.32) | — | |
| SCHEMBL10072333 | 0.90 | — | — | |
| SCHEMBL10072319 | 0.90 | PDK2 (0.32) | — | |
| SCHEMBL883522 | 0.90 | F2 (0.31) | — | |
| SCHEMBL883228 | 0.89 | PDK2 (0.30) | — | |
| SCHEMBL875201 | 0.89 | OPRM1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619189-A1 | ISOXAZOLINE OXIMES AS ANTIPARASITIC AGENTS | Zoetis LLC (US) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038851-A1 | ISOXAZOLINE OXIMES AS ANTIPARASITIC AGENTS | PFIZER INC. (US) | 2012-03-29 | — | — | WO | disclosed |