SCHEMBL8756864

SCHEMBL8756864

Cc1cnc2c(ccc3cccnc32)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 6/20 1.00
CCR8 P51685 6/20 1.00
CCR5 P51681 4/20 1.00
LMNA P02545 4/20 0.61
KDM4E B2RXH2 3/20 0.61
MAPT P10636 2/20 0.61
HTT P42858 2/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
TDP1 Q9NUW8 2/20 0.61
GMNN O75496 1/20 0.61
TP53 P04637 1/20 0.61
HSP90AA1 P07900 1/20 0.61
MMP2 P08253 1/20 0.61
CYP3A4 P08684 1/20 0.61
CYP2D6 P10635 1/20 0.61
MMP9 P14780 1/20 0.61
ALOX15 P16050 1/20 0.61
TSHR P16473 1/20 0.61
NFKB1 P19838 1/20 0.61
MMP8 P22894 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30492679 1.00 CCR1 (1.00) CCR1CCR8CCR5LMNAKDM4E
SCHEMBL30492603 0.85 CCR1 (1.00) CCR1CCR8CCR5KDM4ETDP1
SCHEMBL686948 0.85 CCR1 (1.00) CCR1CCR8CCR5KDM4ETDP1
SCHEMBL11648732 0.85 CCR1 (0.72) CCR1CCR8CCR5LMNAKDM4E
Phenanthroline SCHEMBL1420002 0.81 LMNA (0.76) CCR1CCR8CCR5LMNAKDM4E
Phenanthroline SCHEMBL29635370 0.81 CCR1 (0.94) CCR1CCR8CCR5LMNAKDM4E
Phenanthroline SCHEMBL27885493 0.81 CCR1 (0.94) CCR1CCR8CCR5LMNAKDM4E
SCHEMBL23954363 0.80 CCR1 (0.67) CCR1CCR8CCR5LMNAKDM4E
SCHEMBL2619133 0.80 CCR1 (0.67) CCR1CCR8CCR5KDM4EPSMD14
SCHEMBL18774829 0.79 CCR1 (0.65) CCR1CCR8CCR5LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 276 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167144-A1 PREPARATION AND ITS APPLICATION OF A CYANIDE-BRIDGED METAL ORGANIC COMPOUND WITH INTRAMOLECULAR MAGNETIC TRANSFORMATION Hubei Jingmen Industrial Technology Research Institute Co., Ltd. (CN) 2023-06-01 US claimed
CN-111718381-A Osmium metal organic compound containing polypyridine ligand and preparation method and application thereof 荆楚理工学院 2020-09-29 CN claimed
CN-111518145-A Cyanide-bridged metal organic compound with intramolecular magnetic transformation, and preparation method and application thereof 荆楚理工学院 2020-08-11 CN claimed
EP-0559288-B1 Preparation of alternating olefin/carbon monoxide copolymers by means of a heterogeneous supported catalyst ENICHEM SPA (IT) 1997-06-25 EP claimed
EP-0559289-B1 Heterogeneous catalyst for preparing alternating olefin/carbon monoxide copolymers ENICHEM SPA (IT) 1997-06-25 EP claimed
EP-0560456-B1 Novel homogeneous catalytic system and process for copolymerizing olefins with carbon monoxide ENICHEM SPA (IT) 1997-06-18 EP claimed
EP-0560455-B1 Catalytic system and process for copolymerizing carbon monoxide with one or more olefins ENICHEM SPA (IT) 1997-05-14 EP claimed
US-5369073-A Homogeneous catalytic system and process for copolymerizing olefins with carbon monoxide ENICHEM S.P.A. (IT) 1994-11-29 US claimed
US-5346873-A Catalytic system and system for copolymerizing carbon monoxide with one or more olefins ENICHEM S.P.A. (IT) 1994-09-13 US claimed
US-5324701-A Heterogeneous catalyst for preparing alternating olefin/carbon monoxide copolymers ENICHEM S.P.A. (IT) 1994-06-28 US claimed
US-5314856-A Preparation of alternating olefin/carbon monoxide copolymers by means of a heterogeneous supported catalyst ENICHEM S.P.A. (IT) 1994-05-24 US claimed
EP-0560455-A1 Catalytic system and process for copolymerizing carbon monoxide with one or more olefins ENICHEM S.p.A. (IT) 1993-09-15 EP claimed
EP-0560456-A1 Novel homogeneous catalytic system and process for copolymerizing olefins with carbon monoxide ENICHEM S.p.A. (IT) 1993-09-15 EP claimed
EP-0559289-A1 Heterogeneous catalyst for preparing alternating olefin/carbon monoxide copolymers ENICHEM S.p.A. (IT) 1993-09-08 EP claimed
EP-0559288-A1 Preparation of alternating olefin/carbon monoxide copolymers by means of a heterogeneous supported catalyst ENICHEM S.p.A. (IT) 1993-09-08 EP claimed
US-4086229-A Dinitrosyldihalo complexes of molybdenum or tungsten PHILLIPS PETROLEUM COMPANY (US) 1978-04-25 US claimed
EP-3892611-B1 METHOD FOR PRODUCING FLUOROVINYL AMIDE COMPOUND DAIKIN IND LTD (JP) 2026-01-28 EP disclosed
US-20250214936-A1 METHOD FOR PRODUCING FLUOROVINYL AMIDE COMPOUND DAIKIN INDUSTRIES, LTD. (JP) 2025-07-03 US disclosed
EP-0559289-A1 Heterogeneous catalyst for preparing alternating olefin/carbon monoxide copolymers ENICHEM S.p.A. (IT) 1993-09-08 EP disclosed
US-4086229-A Dinitrosyldihalo complexes of molybdenum or tungsten PHILLIPS PETROLEUM COMPANY (US) 1978-04-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214936-A1 METHOD FOR PRODUCING FLUOROVINYL AMIDE COMPOUND RB1, KRAS, NRAS CCR1 2959/4885CCR8 3853/4885CCR5 4698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.