⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1999102 | 1.00 | — | — | |
| SCHEMBL1995107 | 1.00 | — | — | |
| SCHEMBL22230499 | 0.78 | — | — | |
| SCHEMBL963465 | 0.78 | CTSK (0.53) | — | |
| SCHEMBL1999790 | 0.78 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL2058674 | 0.78 | CTSK (0.53) | — | |
| SCHEMBL9425855 | 0.78 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL327825 | 0.78 | CTSK (0.53) | — | |
| SCHEMBL881290 | 0.76 | TDP1 (0.36) | — | |
| SCHEMBL12462615 | 0.76 | TDP1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160257676-A1 | Aminoisoquinoline Derivatives as Protein Kinase Inhibitors | Eternity Bioscience Inc. (US) | 2016-09-08 | — | — | US | disclosed |
| WO-2014082379-A9 | SPIRO RING COMPOUND AS HEPATITIS C VIRUS (HCV) INHIBITOR AND USES THEREOF FIELD OF THE INVENTION | SUNSHINE LAKE PHARMA CO.,LTD. (CN) | 2016-02-25 | — | — | WO | disclosed |
| EP-2895166-A1 | AMINOISOQUINOLINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | Eternity Bioscience Inc. (US) | 2015-07-22 | — | — | EP | disclosed |
| WO-2014043296-A1 | AMINOISOQUINOLINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | Eternity Bioscience Inc. (US) | 2014-03-20 | — | — | WO | disclosed |
| US-8329159-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-12-11 | — | — | US | disclosed |
| WO-2012068234-A2 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2012-05-24 | — | — | WO | disclosed |
| WO-2011149856-A1 | INHIBITORS OF HCV NS5A | PRESIDIO PHARMACEUTICALS, INC. (US) | 2011-12-01 | — | — | WO | disclosed |