Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7777718 | 0.87 | VCAM1 (0.49) | VCAM1SMN1; SMN2KMT2AMAPTTDP1 | |
| SCHEMBL1584481 | 0.80 | TSHR (0.46) | VCAM1SMN1; SMN2KMT2AMAPTTDP1 | |
| SCHEMBL27750330 | 0.79 | TSHR (0.49) | VCAM1SMN1; SMN2KMT2AMAPTTDP1 | |
| SCHEMBL13520113 | 0.78 | TDP1 (0.50) | SMN1; SMN2KMT2AMAPTTDP1TSHR | |
| SCHEMBL5309337 | 0.78 | TSHR (0.44) | VCAM1SMN1; SMN2KMT2AMAPTTDP1 | |
| SCHEMBL31305226 | 0.78 | TDP1 (0.50) | SMN1; SMN2KMT2AMAPTTDP1TSHR | |
| SCHEMBL543121 | 0.78 | TSHR (0.44) | VCAM1SMN1; SMN2KMT2AMAPTTDP1 | |
| SCHEMBL3710523 | 0.78 | KMT2A (0.52) | VCAM1SMN1; SMN2KMT2AMAPTTDP1 | |
| SCHEMBL5310060 | 0.78 | KMT2A (0.47) | VCAM1SMN1; SMN2KMT2AMAPTTDP1 | |
| SCHEMBL19071961 | 0.75 | VCAM1 (0.79) | VCAM1SMN1; SMN2MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775137-A1 | SACCHARINE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1997-05-28 | — | — | EP | disclosed |
| EP-0775123-A2 | SACCHARIN DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1997-05-28 | — | — | EP | disclosed |
| EP-0775124-A1 | HERBICIDAL SACCHARIN CARBOXYLIC ACID DERIVATIVES AND METHOD FOR THEIR PREPARATION | BASF AKTIENGESELLSCHAFT (DE) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996005198-A1 | SACCHARINE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1996-02-22 | — | — | WO | disclosed |
| WO-1996005184-A1 | HERBICIDAL SACCHARIN CARBOXYLIC ACID DERIVATIVES AND METHOD FOR THEIR PREPARATION | BASF AKTIENGESELLSCHAFT (DE) | 1996-02-22 | — | — | WO | disclosed |
| WO-1996005182-A2 | SACCHARIN DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1996-02-22 | — | — | WO | disclosed |