Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27468094 | 1.00 | MAPT (0.51) | MAPTKMT2AMEN1MAPK1NPC1 | |
| SCHEMBL11592383 | 0.88 | NPC1 (0.50) | MAPTKMT2AMEN1MAPK1NPC1 | |
| SCHEMBL11592388 | 0.86 | MAPT (0.47) | MAPTKMT2AMEN1MAPK1NPC1 | |
| SCHEMBL4876482 | 0.85 | ALDH1A1 (0.49) | MAPTKMT2AMEN1MAPK1NPC1 | |
| SCHEMBL513491 | 0.85 | TSHR (0.49) | MAPTKMT2AMEN1MAPK1NPC1 | |
| SCHEMBL27937254 | 0.84 | MAPT (0.53) | MAPTKMT2AMEN1MAPK1NPC1 | |
| SCHEMBL11027105 | 0.84 | KMT2A (0.54) | MAPTKMT2AMEN1MAPK1NPC1 | |
| SCHEMBL27483144 | 0.82 | MAPT (0.48) | MAPTKMT2AMEN1MAPK1NPC1 | |
| SCHEMBL8429897 | 0.81 | MAPT (0.50) | MAPTKMT2AMEN1MAPK1NPC1 | |
| SCHEMBL4312444 | 0.81 | NPC1 (0.44) | MAPTKMT2AMEN1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116875585-A | Preparation method of lipase microreactor and application of lipase microreactor in preparation of functional ester | 中国农业科学院油料作物研究所 | 2023-10-13 | — | — | CN | disclosed |
| EP-0592552-B1 | CHIRAL PHOSPHOLANES VIA CHIRAL 1,4-DIOL CYCLIC SULFATES | DU PONT (US) | 1997-05-28 | — | — | EP | disclosed |
| US-5596114-A | ENANTIOSELECTIVE HYDROGENATION CATALYSTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-01-21 | — | — | US | disclosed |
| US-5565593-A | FERROCENYL-1,1'-BIS(DIETHYPHOSPHONITE); CHEMICAL INTERMEDIATES FOR PREPERATION OF PHOSPHOLANE LIGANDS AND CHIRAL COMPLEXES, USEFUL AS CATALYSTS FOR CARRYING OUT ENANTIOSELECTIVE REACTIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-10-15 | — | — | US | disclosed |
| US-5559267-A | ENANTIOMORPHS, STEREOCHEMICAL CONTROL AND ASSYMETRIC INDUCTION, HYDROGENATION OF UNSATURATED ESTERS, COORDINATION CATALYSTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-09-24 | — | — | US | disclosed |
| US-5532395-A | HYDROGENATION CATALYSTS ) | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-07-02 | — | — | US | disclosed |
| US-5386061-A | Reacting a bis(primary phosphine in the presence of a strong base with a cyclic sulfate; cyclization | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-01-31 | — | — | US | disclosed |
| US-5329015-A | Catalysts for stereospecific reactions | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-07-12 | — | — | US | disclosed |
| WO-1993001199-A1 | CHIRAL PHOSPHOLANES VIA CHIRAL 1,4-DIOL CYCLIC SULFATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-01-21 | — | — | WO | disclosed |
| US-5171892-A | Chiral phospholanes via chiral 1,4-diol cyclic sulfates | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-12-15 | — | — | US | disclosed |