Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 8/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5478179 | 0.84 | AHR (0.33) | AHRKIF11 | |
| SCHEMBL1752066 | 0.83 | AHR (0.48) | AHRTSHRKIF11 | |
| SCHEMBL5478043 | 0.76 | CYP1A2 (0.44) | — | |
| SCHEMBL316417 | 0.75 | AHR (0.50) | AHRKIF11 | |
| SCHEMBL31085202 | 0.75 | AHR (0.50) | AHRKIF11 | |
| SCHEMBL7270519 | 0.72 | TSHR (0.68) | AHRTSHRKIF11 | |
| SCHEMBL12749096 | 0.72 | AHR (0.42) | AHR | |
| SCHEMBL17543892 | 0.70 | AHR (0.35) | AHRKIF11 | |
| SCHEMBL1702342 | 0.69 | AHR (0.58) | AHR | |
| SCHEMBL31457665 | 0.69 | AHR (0.33) | AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670665-A | Process for the preparation of fluorine-substituted aminobenzodioxoles and -benzodioxanes and new intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | disclosed |
| EP-0537519-B1 | Method for the preparation of fluoro substituted aminobenzodioxoles and -benzodioxanes and intermediates | BAYER AG (DE) | 1997-06-04 | — | — | EP | disclosed |
| US-5559253-A | Process for the preparation of fluorine-substituted aminobenzodioxles and -benzodioxanes and new intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1996-09-24 | — | — | US | disclosed |
| EP-0537519-A1 | Method for the preparation of fluoro substituted aminobenzodioxoles and -benzodioxanes and intermediates | BAYER AG (DE) | 1993-04-21 | — | — | EP | disclosed |