SCHEMBL8760144

SCHEMBL8760144

N#Cc1cccnc1Nc1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 7/20 0.68
ALDH1A1 P00352 6/20 0.68
SMN1; SMN2 Q16637 5/20 0.68
NPC1 O15118 4/20 0.68
RAB9A P51151 4/20 0.68
CYP1A2 P05177 2/20 0.68
CYP2D6 P10635 2/20 0.68
CYP2C9 P11712 2/20 0.68
CYP2C19 P33261 2/20 0.68
CYP3A4 P08684 1/20 0.68
POLB P06746 1/20 0.68
L3MBTL1 Q9Y468 2/20 0.61
TDP1 Q9NUW8 1/20 0.61
CASP3 P42574 1/20 0.61
NPSR1 Q6W5P4 1/20 0.61
SENP8 Q96LD8 1/20 0.61
SENP7 Q9BQF6 1/20 0.61
SENP6 Q9GZR1 1/20 0.61
BCL6 P41182 1/20 0.53
DHODH Q02127 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27241721 0.81 HPGD (0.62) HPGDALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL27886355 0.81 SYK (0.63) HPGDALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL29420826 0.81 HPGD (0.62) HPGDALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL20552307 0.81 HPGD (0.62) HPGDALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL29888286 0.81 HPGD (0.62) HPGDALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL23388827 0.81 HPGD (0.62) HPGDALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL27241737 0.81 HPGD (0.54) HPGDALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL20553261 0.79 HPGD (0.63) HPGDALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL20240562 0.78 ALDH1A1 (0.69) HPGDALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL20627510 0.77 HPGD (0.50) HPGDALDH1A1SMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0476607-A2 2-Anilino-cyanopyridines and their use for pest control BASF Aktiengesellschaft (DE) 1992-03-25 EP claimed
US-5081133-A 2-ANILINOCYANOPYRIDINES HAVING FUNGICIDAL PROPERTIES BASF AKTIENGESELLSCHAFT (DE) 1992-01-14 US claimed
EP-0384311-A1 2-Anilinocyano pyridines and fungicides containing them BASF Aktiengesellschaft (DE) 1990-08-29 EP claimed
JP-4270266-A None JP disclosed
EP-0617891-B1 Process for combatting agricultural pests and 2-anilin-pyridines BASF AG (DE) 1997-05-28 EP disclosed
US-5569765-A 2-anilinopyridine pesticides BASF AKTIENGESELLSCHAFT (DE) 1996-10-29 US disclosed
US-5453432-A Anilinopyridines BASF AKTIENGESELLSCHAFT (DE) 1995-09-26 US disclosed
EP-0617891-A1 Process for combatting agricultural pests and 2-anilin-pyridines BASF Aktiengesellschaft (DE) 1994-10-05 EP disclosed
JP-H04270266-A 2-ANILINOCYANOPYRIDINE AND EXTERMINATION OF HARMFUL ORGANISM USING THE SAME BASF AG 1992-09-25 JP disclosed
EP-0476607-A2 2-Anilino-cyanopyridines and their use for pest control BASF Aktiengesellschaft (DE) 1992-03-25 EP disclosed
EP-0476607-A2 2-Anilino-cyanopyridines and their use for pest control BASF Aktiengesellschaft (DE) 1992-03-25 EP disclosed
EP-0476607-A2 2-Anilino-cyanopyridines and their use for pest control BASF Aktiengesellschaft (DE) 1992-03-25 EP disclosed
US-5081133-A 2-ANILINOCYANOPYRIDINES HAVING FUNGICIDAL PROPERTIES BASF AKTIENGESELLSCHAFT (DE) 1992-01-14 US disclosed
US-5081133-A 2-ANILINOCYANOPYRIDINES HAVING FUNGICIDAL PROPERTIES BASF AKTIENGESELLSCHAFT (DE) 1992-01-14 US disclosed
EP-0384311-A1 2-Anilinocyano pyridines and fungicides containing them BASF Aktiengesellschaft (DE) 1990-08-29 EP disclosed
EP-0384311-A1 2-Anilinocyano pyridines and fungicides containing them BASF Aktiengesellschaft (DE) 1990-08-29 EP disclosed
EP-0384311-A1 2-Anilinocyano pyridines and fungicides containing them BASF Aktiengesellschaft (DE) 1990-08-29 EP disclosed