Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1914583 | 0.84 | GABRA1 (0.43) | GABRA1GABRB2GAAMEN1KMT2A | |
| SCHEMBL2162474 | 0.81 | GABRA1 (0.42) | GABRA1GABRB2TSHRGAAKDM4E | |
| SCHEMBL22355711 | 0.80 | GABRA1 (0.54) | GABRA1GABRB2GAAMEN1KMT2A | |
| SCHEMBL31185609 | 0.80 | GABRA1 (0.43) | GABRA1GABRB2GAAMEN1KMT2A | |
| SCHEMBL8655295 | 0.80 | GABRA1 (0.43) | GABRA1GABRB2GAAMEN1KMT2A | |
| SCHEMBL2170193 | 0.80 | GABRA1 (0.43) | GABRA1GABRB2TSHRGAAMEN1 | |
| SCHEMBL8855696 | 0.79 | TSHR (0.46) | TSHRNISCHLRRK2ALDH1A1MAPT | |
| SCHEMBL9686700 | 0.79 | GABRA1 (0.42) | GABRA1GABRB2TSHRMEN1KMT2A | |
| SCHEMBL11967122 | 0.77 | TSHR (0.45) | GABRA1GABRB2TSHRGAANISCH | |
| SCHEMBL21533235 | 0.77 | AKR1B1 (0.37) | GABRA1GABRB2TSHRGAANISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543238-B1 | 3-Isoxazolylphenyl-compounds, their preparation and application | BASF AG (DE) | 1997-06-04 | — | — | EP | disclosed |
| US-5256666-A | Pesticides | BASF AKTIENGESELLSCHAFT (DE) | 1993-10-26 | — | — | US | disclosed |
| EP-0543238-A1 | 3-Isoxazolylphenyl-compounds, their preparation and application | BASF Aktiengesellschaft (DE) | 1993-05-26 | — | — | EP | disclosed |