SCHEMBL8760381

SCHEMBL8760381

CCOC(=O)C1=NN(c2ccc(C(=O)O)cc2)C(=O)C1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.79
KDM4E B2RXH2 1/20 0.75
NPC1 O15118 1/20 0.75
MAPT P10636 1/20 0.75
RAB9A P51151 1/20 0.75
POLB P06746 2/20 0.54
ATM Q13315 1/20 0.45
HTT P42858 3/20 0.44
HPGD P15428 2/20 0.44
ALDH1A1 P00352 1/20 0.44
HSP90AA1 P07900 1/20 0.44
CACNA1B Q00975 1/20 0.44
APBA1 Q02410 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
NR3C2 P08235 1/20 0.43
MAPK1 P28482 1/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
KAT8 Q9H7Z6 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3407816 0.88 GAA (1.00) GAAKDM4ENPC1MAPTRAB9A
Methyl Alcohol SCHEMBL11812087 0.87 GAA (0.97) GAAKDM4ENPC1MAPTRAB9A
SCHEMBL22121919 0.86 MAPT (0.77) GAAKDM4ENPC1MAPTRAB9A
SCHEMBL8386526 0.82 MAPT (0.72) GAAKDM4ENPC1MAPTRAB9A
SCHEMBL13597571 0.82 POLB (0.76) GAAKDM4ENPC1MAPTRAB9A
SCHEMBL4661824 0.80 MAPT (0.61) GAAKDM4ENPC1MAPTRAB9A
SCHEMBL6953402 0.80 GAA (0.60) GAAKDM4ENPC1MAPTRAB9A
SCHEMBL14608264 0.80 GAA (0.54) GAAKDM4ENPC1MAPTRAB9A
SCHEMBL643536 0.78 POLB (0.75) GAAKDM4EMAPTPOLBHTT
SCHEMBL8425552 0.77 POLB (0.55) GAAKDM4ENPC1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0524594-B1 Solid particle dispersions of filter dyes for photographic elements EASTMAN KODAK CO (US) 1997-06-11 EP disclosed
US-5582962-A COLLOID LAYERS COMPRISING A DISPERSE DYE PARTICLES KONICA CORPORATION (JP) 1996-12-10 US disclosed
EP-0679935-A2 Silver halide photographic light-sensitive material and the processing method thereof KONICA CORPORATION (JP) 1995-11-02 EP disclosed
US-5340707-A Containing specified pyrazolone dye; storage stability KONICA CORPORATION (JP) 1994-08-23 US disclosed
US-5266454-A Furan methine dyes EASTMAN KODAK COMPANY (US) 1993-11-30 US disclosed
EP-0524594-A1 Solid particle dispersions of filter dyes for photographic elements EASTMAN KODAK COMPANY (US) 1993-01-27 EP disclosed
EP-0021513-B1 PHOTOGRAPHIC SILVER HALIDE MATERIALS CONTAINING DISPERSED LIGHT-ABSORBING MEROSTYRYL DYES AGFA-GEVAERT N.V. (BE) 1984-03-21 EP disclosed
US-4311787-A Photographic silver halide materials containing dispersed light-absorbing merostyryl dyes AGFA-GEVAERT, N.V. (BE) 1982-01-19 US disclosed
EP-0021513-A1 Photographic silver halide materials containing dispersed light-absorbing merostyryl dyes AGFA-GEVAERT N.V. (BE) 1981-01-07 EP disclosed