SCHEMBL8760508

SCHEMBL8760508

CCCCC/C=C\C/C=C\CCCCCCCCOC(=O)C(C)OC(=O)[C@@H]1CCC(=O)N1

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.44
DAGLA Q9Y4D2 1/20 0.44
FAAH O00519 1/20 0.38
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8749016 0.91 CNR1 (0.51) CNR1DAGLA
SCHEMBL8762005 0.91 CNR1 (0.51) CNR1DAGLA
SCHEMBL7631788 0.88 CNR1 (0.47) CNR1DAGLAFAAHMEN1ALDH1A1
SCHEMBL10603194 0.87 CNR1 (0.42) CNR1DAGLAFAAHALDH1A1MAPT
SCHEMBL17511719 0.85 CNR1 (0.44) CNR1DAGLAFAAH
SCHEMBL8748982 0.85 CNR1 (0.51) CNR1DAGLAFAAH
SCHEMBL10353256 0.83 CNR1 (0.44) CNR1DAGLAFAAH
SCHEMBL10352981 0.83 CNR1 (0.44) CNR1DAGLAFAAH
SCHEMBL10353307 0.83 CNR1 (0.44) CNR1DAGLAFAAH
SCHEMBL10353702 0.83 CNR1 (0.44) CNR1DAGLAFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0342056-B1 Cosmetic composition UNILEVER PLC (GB) 1994-08-17 EP claimed
EP-0277428-B1 Cosmetic composition UNILEVER PLC (GB) 1994-03-23 EP claimed
EP-0342054-B1 Cosmetic composition UNILEVER PLC (GB) 1993-11-03 EP claimed
US-4774255-A SKIN DISORDERS LEVER BROTHERS COMPANY (US) 1988-09-27 US claimed
EP-0446047-B1 Benzisothiazolinone-1-dioxide derivatives as elastase inhibitors UNILEVER PLC (GB) 1997-06-11 EP disclosed
EP-0572167-B1 Cosmetic composition UNILEVER PLC (GB) 1996-10-09 EP disclosed
US-5559092-A HAIR GROWTH, GLUTAMINE DIPEPTIDE CHESEBROUGH-POND'S USA CO. DIVISION OF CONOPCO, INC. (US) 1996-09-24 US disclosed
EP-0490581-B1 Cosmetic composition UNILEVER PLC (GB) 1996-05-22 EP disclosed
EP-0517371-B1 Hair growth composition containing citric acid esters UNILEVER PLC (GB) 1996-01-10 EP disclosed
US-5411978-A Aging resistance, human skin CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1995-05-02 US disclosed
EP-0334585-B1 Cosmetic composition UNILEVER PLC (GB) 1994-09-14 EP disclosed
EP-0342056-B1 Cosmetic composition UNILEVER PLC (GB) 1994-08-17 EP disclosed
EP-0398669-B1 Cosmetic composition UNILEVER PLC (GB) 1994-01-05 EP disclosed
EP-0572167-A1 Cosmestic composition UNILEVER PLC (GB) 1993-12-01 EP disclosed
EP-0571198-A1 Cosmetic composition containing hair-growth promoter UNILEVER PLC (GB) 1993-11-24 EP disclosed
EP-0342054-B1 Cosmetic composition UNILEVER PLC (GB) 1993-11-03 EP disclosed
EP-0348184-B1 COSMETIC COMPOSITION UNILEVER PLC (GB) 1993-03-03 EP disclosed
EP-0335554-B1 COSMETIC COMPOSITION UNILEVER PLC (GB) 1992-07-08 EP disclosed
EP-0490581-A1 Cosmetic composition UNILEVER PLC (GB) 1992-06-17 EP disclosed
EP-0446047-A1 Benzisothiazolinone-1-dioxide derivatives as elastase inhibitors UNILEVER PLC (GB) 1991-09-11 EP disclosed