SCHEMBL8748982

SCHEMBL8748982

CCCCCCC(O)CCCCCCCCCCCOC(=O)C(C)OC(=O)[C@@H]1CCC(=O)N1

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.51
DAGLA Q9Y4D2 1/20 0.51
PTGER4 P35408 4/20 0.37
PTGER3 P43115 3/20 0.37
PTGER2 P43116 3/20 0.37
NAAA Q02083 2/20 0.37
LMNA P02545 1/20 0.36
CCR2 P41597 1/20 0.35
GAA P10253 2/20 0.34
FFAR4 Q5NUL3 1/20 0.34
FFAR1 O14842 1/20 0.34
FAAH O00519 1/20 0.34
MAPK1 P28482 1/20 0.34
HTT P42858 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
ABCB1 P08183 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8749016 0.93 CNR1 (0.51) CNR1DAGLANAAALMNAGAA
SCHEMBL8762005 0.93 CNR1 (0.51) CNR1DAGLANAAALMNAGAA
SCHEMBL10633360 0.86 CNR1 (0.44) CNR1DAGLAPTGER4PTGER3PTGER2
SCHEMBL8760508 0.85 CNR1 (0.44) CNR1DAGLAFAAH
SCHEMBL8762027 0.84 CNR1 (0.54) CNR1DAGLANAAALMNACCR2
SCHEMBL8748644 0.84 CNR1 (0.54) CNR1DAGLANAAALMNACCR2
SCHEMBL7638305 0.84 CNR1 (0.54) CNR1DAGLANAAALMNACCR2
SCHEMBL8761598 0.84 CNR1 (0.44) CNR1DAGLALMNAGAASMN1; SMN2
SCHEMBL8749260 0.81 CNR1 (0.59) CNR1DAGLANAAALMNACCR2
SCHEMBL8749261 0.81 CNR1 (0.59) CNR1DAGLANAAALMNACCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0342056-B1 Cosmetic composition UNILEVER PLC (GB) 1994-08-17 EP claimed
EP-0277428-B1 Cosmetic composition UNILEVER PLC (GB) 1994-03-23 EP claimed
EP-0342054-B1 Cosmetic composition UNILEVER PLC (GB) 1993-11-03 EP claimed
EP-0342054-A2 Cosmetic composition UNILEVER PLC (GB) 1989-11-15 EP claimed
EP-0342055-A2 Use of pyroglutamic acid alkyl esters for the manufacture of a medicament for the treatment of ichthyosis UNILEVER PLC (GB) 1989-11-15 EP claimed
EP-0342056-A2 Cosmetic composition UNILEVER PLC (GB) 1989-11-15 EP claimed
EP-0176217-B1 PYROGLUTAMIC ACID ESTERS, THEIR SYNTHESIS AND USE IN TOPICAL PRODUCTS UNILEVER PLC (GB) 1989-06-07 EP claimed
US-4774255-A SKIN DISORDERS LEVER BROTHERS COMPANY (US) 1988-09-27 US claimed
EP-0277428-A2 Cosmetic composition UNILEVER PLC (GB) 1988-08-10 EP claimed
EP-0446047-B1 Benzisothiazolinone-1-dioxide derivatives as elastase inhibitors UNILEVER PLC (GB) 1997-06-11 EP disclosed
EP-0571198-B1 Cosmetic composition containing hair-growth promoter UNILEVER PLC (GB) 1997-03-19 EP disclosed
EP-0572167-B1 Cosmetic composition UNILEVER PLC (GB) 1996-10-09 EP disclosed
US-5559092-A HAIR GROWTH, GLUTAMINE DIPEPTIDE CHESEBROUGH-POND'S USA CO. DIVISION OF CONOPCO, INC. (US) 1996-09-24 US disclosed
EP-0490581-B1 Cosmetic composition UNILEVER PLC (GB) 1996-05-22 EP disclosed
EP-0335554-A2 Cosmetic composition UNILEVER PLC (GB) 1989-10-04 EP disclosed
EP-0334586-A1 Carbohydrate lactam derivatives and their use in cosmetic compositions UNILEVER PLC (GB) 1989-09-27 EP disclosed
EP-0334585-A2 Cosmetic composition UNILEVER PLC (GB) 1989-09-27 EP disclosed
US-4832946-A CELL CULTURE FOR HAIR GROWTH CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC., A CORP. OF NY 1989-05-23 US disclosed
EP-0277428-A2 Cosmetic composition UNILEVER PLC (GB) 1988-08-10 EP disclosed
EP-0272920-A1 Cosmetic composition UNILEVER PLC (GB) 1988-06-29 EP disclosed